{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:57:41Z","timestamp":1777859861762,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Patient Center Outcomes Research Institute, University of Missouri","award":["R24HS022140"],"award-info":[{"award-number":["R24HS022140"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Patient Experience"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Medication nonadherence is a public health issue that contributes to poor health outcomes and health-care costs. Factors influencing long-term medication adherence are known; however, little is known about short-course medication adherence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study examined patient perspectives on adherence and factors that influence adherence to short-course pharmacotherapy in diarrhea-predominant irritable bowel syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>Twenty-seven participants were interviewed to identify their perceptions of barriers and facilitators to thrice-daily, 14-day rifaximin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Participants were primarily female (89%), aged 18 to 65 years. Sixty-eight percent of interviewees were identified as \u201clow-adherers,\u201d meaning the percentage of days with correct daily dosing of rifaximin was &lt;80%. The final coding framework identified social\/economic-related (family support and medication expense), system-related (relationship with provider and medication knowledge), condition-related (symptom severity), therapy-related (inconvenient dosing), and patient-related (forgetfulness and busyness of daily life) factors that influenced adherence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The resulting patient perspectives highlight a diverse set of factors that influence short-course adherence and the need for tailored interventions that address these various factors resulting in enhanced patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2374373519882230","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T08:31:46Z","timestamp":1571819506000},"page":"726-733","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Patient Perspectives on Short-Course Pharmacotherapy: Barriers and Facilitators to Medication Adherence"],"prefix":"10.1177","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8547-9724","authenticated-orcid":false,"given":"LeeAnne B","family":"Sherwin","sequence":"first","affiliation":[{"name":"Sinclair School of Nursing, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Ross","sequence":"additional","affiliation":[{"name":"Sinclair School of Nursing, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Matteson-Kome","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Missouri Healthcare, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Bechtold","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Missouri Healthcare, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chelsea","family":"Deroche","sequence":"additional","affiliation":[{"name":"Sinclair School of Nursing, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bonnie","family":"Wakefield","sequence":"additional","affiliation":[{"name":"Sinclair School of Nursing, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"key":"bibr1-2374373519882230","doi-asserted-by":"crossref","unstructured":"Brown MT, Bussell JK. 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