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Participants were recruited from United States patient support groups. Participants had received or were receiving ovulation induction (OI) with or without intrauterine insemination (IUI), with or without subsequent in vitro fertilization (IVF), or IVF with no other previous infertility treatment. Live birth was achieved by 62% of participants. Compared with participants treated with OI\/IUI only, participants who underwent OI\/IUI followed by \u22651 IVF cycle were less likely to consider discontinuing care (64% vs 77%; P\u2009=\u2009.014) or to discontinue treatment without achieving a pregnancy (40% vs 58%; P\u2009=\u2009.004). The most commonly cited reasons for treatment discontinuation were financial (62%) and psychological burden\/treatment fatigue (58%). Expected versus actual time to pregnancy differed greatly. Continued desire for a child (60%) was the most frequently cited reason for continuing or resuming treatment. Expanded access to treatment, counseling and fostering realistic expectations regarding cumulative time to pregnancy may reduce treatment discontinuation.<\/jats:p>","DOI":"10.1177\/23743735241229380","type":"journal-article","created":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T02:49:02Z","timestamp":1709002142000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Identifying Factors Associated with Discontinuation of Infertility Treatment Prior to Achieving Pregnancy: Results of a Nationwide Survey"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3271-7762","authenticated-orcid":false,"given":"Barbara","family":"Collura","sequence":"first","affiliation":[{"name":"RESOLVE: The National Infertility Association, McLean, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke","family":"Hayward","sequence":"additional","affiliation":[{"name":"EMD Serono, Rockland, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krysten A","family":"Modrzejewski","sequence":"additional","affiliation":[{"name":"EMD Serono, Rockland, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert L","family":"Mottla","sequence":"additional","affiliation":[{"name":"Shady Grove Fertility Center, Annapolis, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin S","family":"Richter","sequence":"additional","affiliation":[{"name":"Fertility Science Consulting, Silver Spring, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison B","family":"Catherino","sequence":"additional","affiliation":[{"name":"EMD Serono, Rockland, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"bibr1-23743735241229380","unstructured":"US Department of Health and Human Services. 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