{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:56:49Z","timestamp":1777859809043,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"SetPoint Medical"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Patient Experience"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Despite broadening treatment options for rheumatoid arthritis (RA), challenges and unmet needs remain. This study aimed to characterize patient preferences with current pharmacologic treatments and impressions of an implantable neuroimmune modulation device. A patient survey was conducted, combined with a discrete choice experiment that included 12 choice sets, containing a device profile and drug profile, featuring 8 attributes specific to each. In total, 354 completed surveys were included, 74% female, 79% &lt;60 years, stratified into Biologic Na\u00efve (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009103); Biologic-Experienced-I (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009151); and Biologic-Experienced-II (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009100). Lack of efficacy was the primary reason for treatment discontinuation of conventional disease-modifying antirheumatic drugs (DMARDs) and biologic or targeted synthetic DMARDs. Initial impression of device-based treatment was \u201cPositive\u201d or \u201cExtremely Positive\u201d by 45% and preference ranked higher than current drug treatment options for both Biologic Experienced groups. Key drivers of treatment preference included out-of-pocket cost, symptom improvement, physical function and fatigue, and irreversible joint damage protection. RA patients were accepting of a novel neuroimmune modulation approach, including a surgically implanted device, meeting identified attributes and expectations of safety and efficacy as observed in controlled trials.\n                  <\/jats:p>","DOI":"10.1177\/23743735251415236","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T14:18:56Z","timestamp":1769091536000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Patient Preferences for Treatments of Rheumatoid Arthritis: A Discrete Choice Experiment Evaluating Preference for Novel Neuroimmune Modulation Devices"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4959-8819","authenticated-orcid":false,"given":"Jeffrey R.","family":"Curtis","sequence":"first","affiliation":[{"name":"University of Alabama at Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpa","family":"Venkatachalam","sequence":"additional","affiliation":[{"name":"Patient Centered Research, Global Healthy Living Foundation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherry","family":"Danese","sequence":"additional","affiliation":[{"name":"Outcomes Insights"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Ulloa","sequence":"additional","affiliation":[{"name":"Outcomes Insights"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua Fitzgerald","family":"Baker","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"},{"name":"Corporal Michael J. Crescenz VA Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24596"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-017-0078-y"},{"key":"e_1_3_3_4_2","article-title":"Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial","author":"Tesser JRP","year":"2025","unstructured":"Tesser JRP, Crowley AR, Box EJ, et al. Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial. Nat Med. 2025. doi:https:\/\/doi.org\/10.1038\/s41591-025-04114-7. 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J Clin Diagn Res. 2017;11(5):JE06-9.","journal-title":"J Clin Diagn Res"},{"issue":"2","key":"e_1_3_3_11_2","first-page":"75","article-title":"The journey from Likert to forced-choice questionnaires: evidence of the invariance of the item parameters","volume":"35","author":"Morillo D","year":"2019","unstructured":"Morillo D, Abad FJ, Kreitchmann R, et al. The journey from Likert to forced-choice questionnaires: evidence of the invariance of the item parameters. 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A study evaluating adherence and compliance of anti-rheumatic drugs in women suffering from rheumatoid arthritis. J Clin Diagn Res. 2015;9(11):OC01-4.","journal-title":"J Clin Diagn Res"},{"issue":"3","key":"e_1_3_3_24_2","article-title":"The importance of the patients\u2019 experience of RA compared with clinical measures of disease activity","volume":"28","author":"Taylor PC","year":"2010","unstructured":"Taylor PC. The importance of the patients\u2019 experience of RA compared with clinical measures of disease activity. 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