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This study aimed to compare the effectiveness of aloe vera gel, rosemary oil, and their combination with a control intervention in preventing PIs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A triple-blind randomized four arm parallel clinical trial was conducted among 160 orthopedic patients assigned to four groups: aloe vera\u2013rosemary combination, rosemary oil, aloe vera gel, or control (n=40 each). The assigned spray was applied twice daily for 10 days to pressure-prone areas. Outcomes included PI incidence, skin temperature, and pain intensity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The aloe vera\u2013rosemary group demonstrated the lowest incidence of sacral, hip, heel, and total PIs compared with the other groups (p = 0.02, 0.03, 0.03, and 0.009, respectively). Significant reductions in pain intensity were also observed across pressure-prone areas over time (all p &lt; 0.001). Additionally, skin temperature decreased significantly in the intervention groups compared with the control group during follow-up (all p &lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The rosemary oil and aloe vera-rosemary oil combination showed positive effectiveness in preventing PIs; it is recommended for use in the prevention of PIs among orthopedic patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23779608261461045","type":"journal-article","created":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T12:03:11Z","timestamp":1781352191000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Nurse-Applied Aloe Vera and Rosemary Oil Combination on Pressure Injury Prevention in Orthopaedic Surgery: A Triple-Blind Randomized Trial"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0646-8037","authenticated-orcid":false,"given":"Mohamed E.H","family":"Elzeky","sequence":"first","affiliation":[{"name":"Jouf University"},{"name":"Mansoura University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awatef","family":"abdelhamid","sequence":"additional","affiliation":[{"name":"Mansoura University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1372-7199","authenticated-orcid":false,"given":"Basma","family":"Salameh","sequence":"additional","affiliation":[{"name":"Arab American University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0569-7647","authenticated-orcid":false,"given":"Noha F.M.","family":"Shahine","sequence":"additional","affiliation":[{"name":"Mansoura University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal F.","family":"Soliman","sequence":"additional","affiliation":[{"name":"Mansoura University"},{"name":"Mansoura National University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amgad E.","family":"Salem","sequence":"additional","affiliation":[{"name":"Mansoura University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barakat","family":"Sayed Elalfy","sequence":"additional","affiliation":[{"name":"Mansoura University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Hafez Ramadan El-Shaboury","sequence":"additional","affiliation":[{"name":"Mansoura University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,13]]},"reference":[{"issue":"4","key":"e_1_3_7_2_1","first-page":"1139","article-title":"Lack of prophylactic effects of aloe vera gel on radiation induced dermatitis in breast cancer patients","volume":"18","author":"Ahmadloo N.","year":"2017","unstructured":"Ahmadloo N., Kadkhodaei B., Omidvari S., Mosalaei A., Ansari M., Nasrollahi H., Hamedi S. 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