{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:17:45Z","timestamp":1787019465598,"version":"build-2736575974"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000837","name":"University of Nottingham","doi-asserted-by":"crossref","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/501100000837","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2013-2429"],"award-info":[{"award-number":["2013-2429"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000837","name":"University of Nottingham","doi-asserted-by":"crossref","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/501100000837","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2013-2429"],"award-info":[{"award-number":["2013-2429"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Research has suggested that delivery is associated with an increased risk of stroke in women; however, there is a lack of contemporary estimates on the incidence of stroke in and after pregnancy compared with the baseline risk in women of childbearing age in Sweden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>All women aged 15\u201349 years with live births\/stillbirths in 1992\u20132011 were identified from the Swedish Medical Birth Registry linked with the National Patient Registry. First stroke during the study period was identified. Incidence rates per 100,000 person-years and adjusted incidence rate ratios (IRRs) were calculated for antepartum, peripartum and early and late postpartum periods, compared with all other available follow-up time (time before pregnancy and after postpartum) using Poisson regression adjusted for maternal age, education attainment and calendar time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 1,124,541 women, 3094 had a first incident stroke (331 occurred during pregnancy or first 12 weeks postpartum), about half having ischaemic stroke. The incidence was 15.0 per 100,000 person-years (95% confidence interval 14.5\u201315.6) in non-pregnant time. The incidence was lower antepartum (7.3\/100,000 person-years, 6.0\u20138.9; adjusted IRR\u2009=\u20090.7, 0.5\u20130.8) but higher peripartum (314.4\/100,000 person-years, 247.5\u2013399.5; adjusted IRR\u2009=\u200927.3, 21.4\u201334.9) and early postpartum (64.0\/100,000 person-years, 54.1\u201375.7; adjusted IRR\u2009=\u20095.5, 4.6\u20136.6). The increased risk in peripartum was more evident for intracerebral haemorrhage than other types of stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Overall risk of stroke was low in women of childbearing age, but stroke risk peaks in the peripartum and early postpartum periods. Future work should address factors that contribute to this increased risk in order to develop approaches to attenuate risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2396987317706600","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T06:00:18Z","timestamp":1492754418000},"page":"250-256","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["The incidence of first stroke in and around pregnancy: A population-based cohort study from Sweden"],"prefix":"10.1093","volume":"2","author":[{"given":"Lu","family":"Ban","sequence":"first","affiliation":[{"name":"Division of Epidemiology & Public Health, University of Nottingham, Nottingham, UK 1"},{"name":"Centre of Evidence Based Dermatology, Division of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Nottingham, UK 2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyshah","family":"Abdul Sultan","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Public Health, University of Nottingham, Nottingham, UK 1"},{"name":"Arthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Keele, UK 3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olof","family":"Stephansson","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Unit, Department of Medicine Solna and Department of Women\u2019s and Children\u2019s Health, Karolinska Institutet, Stockholm, Sweden 4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila J","family":"Tata","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Public Health, University of Nottingham, Nottingham, UK 1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikola","family":"Sprigg","sequence":"additional","affiliation":[{"name":"Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK 5"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Nelson-Piercy","sequence":"additional","affiliation":[{"name":"Women\u2019s Health Academic Centre, Guy\u2019s and St. Thomas\u2019 NHS Foundation Trust, London, UK 6"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip M","family":"Bath","sequence":"additional","affiliation":[{"name":"Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK 5"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas F","family":"Ludvigsson","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Public Health, University of Nottingham, Nottingham, UK 1"},{"name":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden 7"},{"name":"Department of Paediatrics, \u00d6rebro University Hospital, \u00d6rebro, Sweden 8"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,9,1]]},"reference":[{"key":"2026012113190791600_bibr1-2396987317706600","doi-asserted-by":"crossref","first-page":"e003661","DOI":"10.1161\/JAHA.116.003661","article-title":"Rising stroke incidence in young adults: more epidemiological evidence, more questions to be answered","volume":"5","author":"B\u00e9jot","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"2026012113190791600_bibr2-2396987317706600"},{"key":"2026012113190791600_bibr3-2396987317706600","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1111\/j.1468-1331.2006.01490.x","article-title":"Stroke complicating pregnancy and the puerperium","volume":"13","author":"Liang CC, Chang SD, Lai","year":"2006","journal-title":"Eur J Neurol"},{"key":"2026012113190791600_bibr4-2396987317706600","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1212\/01.wnl.0000228277.84760.a2","article-title":"Intracerebral hemorrhage in pregnancy. 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