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This study examined risk factors for primary intracerebral haemorrhage, separately for lobar and non-lobar intracerebral haemorrhage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>Incidence of intracerebral haemorrhage was studied among 28,416 individuals from the population-based Malm\u00f6 Diet and Cancer cohort. Intracerebral haemorrhage cases were ascertained using the Swedish Hospital Discharge Register and the Stroke Register of Malm\u00f6, validated by review of hospital records and images, and classified by location by a neuroradiologist. Multivariable Cox regression was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three hundred and thirty-three intracerebral haemorrhages occurred, mean follow-up time was 18.4\u2009years. Systolic blood pressure (hazard ratio per 10\u2009mmHg 1.19 [95% confidence interval 1.13\u20131.26], diastolic blood pressure (hazard ratio 1.42 [1.27\u20131.59]), oral anticoagulants (hazard ratio 4.26 [2.17\u20138.38]), smoking (hazard ratio 1.45 [1.14\u20131.87]), living alone (hazard ratio 1.32 [1.04\u20131.69]) and low apolipoprotein B (hazard ratio per 10\u2009mg\/dL: 0.94 [0.90\u20130.99]) were significantly associated with incident intracerebral haemorrhage after multivariable adjustment. Systolic blood pressure, smoking and oral anticoagulants were associated with lobar intracerebral haemorrhage. Systolic blood pressure, diastolic blood pressure, living alone and diabetes were associated with non-lobar intracerebral haemorrhage. Diabetes and diastolic blood pressure showed significantly different relationships with lobar and non-lobar intracerebral haemorrhage. Alcohol, apolipoprotein A1, body mass index, waist circumference, physical activity and education were not independently associated with intracerebral haemorrhage.<\/jats:p>\n                    <jats:p>Discussion and conclusions: Blood pressure, smoking, low apolipoprotein B, oral anticoagulants and living alone were associated with intracerebral haemorrhage. Diabetes was associated with non-lobar intracerebral haemorrhage only. Further research is required on differences between lobar and non-lobar intracerebral haemorrhage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2396987320932069","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T06:43:14Z","timestamp":1591944194000},"page":"278-285","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Risk factors for intracerebral haemorrhage \u2013 Results from a prospective population-based study"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7720-3701","authenticated-orcid":false,"given":"Edith H","family":"Svensson","sequence":"first","affiliation":[{"name":"Cardiovascular Research \u2013 Epidemiology, Department of Clinical Sciences, Lund University, Malm\u00f6, Sweden 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