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We investigated whether characteristics of the ICH itself were associated with uncontrolled BP at follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Subjects were consecutive patients aged \u2a7e18\u2009years with primary ICH enrolled in the prospective longitudinal ICH study at Massachusetts General Hospital between 1994 and 2015. We assessed the prevalence of uncontrolled BP (mean BP \u2a7e140\/90\u2009mmHg) 6\u2009months after index event. We used multivariable logistic regression models to assess the effect of hematoma location, volume, and event year on uncontrolled BP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 1492 survivors, ICH was lobar in 624 (42%), deep in 749 (50%), cerebellar in 119 (8%). Lobar ICH location was associated with increased risk for uncontrolled BP after 6\u2009months (OR 1.35; 95% CI [1.08\u20131.69]). On average, lobar ICH survivors were treated with fewer antihypertensive drugs compared to the rest of the cohort: 2.1\u2009\u00b1\u20091.1 vs 2.5\u2009\u00b1\u20091.2 (p\u2009&amp;lt;\u20090.001) at baseline and 1.8\u2009\u00b1\u20091.2 vs. 2.4\u2009\u00b1\u20091.2 (p\u2009&amp;lt;\u20090.001) after 6\u2009months follow-up. After adjustment for the number of antihypertensive drugs prescribed, the association of lobar ICH location with risk of uncontrolled BP was eliminated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>ICH survivors with lobar hemorrhage were more likely to have uncontrolled BP after 6\u2009months follow-up. This appears to be a result of being prescribed fewer antihypertensive medications. Future treatment strategies should focus on aggressive BP control after ICH independent of hemorrhage location.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23969873221094412","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T07:58:52Z","timestamp":1651046332000},"page":"280-288","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Lobar intracerebral hemorrhage and risk of subsequent uncontrolled blood pressure"],"prefix":"10.1093","volume":"7","author":[{"given":"Evangelos Pavlos","family":"Myserlis","sequence":"first","affiliation":[{"name":"Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA 1"},{"name":"Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 2"},{"name":"Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA 3"},{"name":"Henry 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Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 2"},{"name":"Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA 3"},{"name":"Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA 4"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3291-2958","authenticated-orcid":false,"given":"Kay-Cheong","family":"Teo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, HK, China SAR 5"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bailey E.","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA 1"},{"name":"Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 2"},{"name":"Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA 3"},{"name":"Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA 4"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lansing","family":"Sugita","sequence":"additional","affiliation":[{"name":"Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA 1"},{"name":"Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 2"},{"name":"Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA 4"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew D","family":"Warren","sequence":"additional","affiliation":[{"name":"Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 2"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua N","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA 6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmut Edip","family":"Gurol","sequence":"additional","affiliation":[{"name":"Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 2"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Viswanathan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 2"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven M","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 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