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Previous research on nutrition status and post-intracerebral hemorrhage (ICH) outcomes, however, is limited and conflicting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>Monocenter study of patients with spontaneous deep or lobar ICH from a longitudinal cohort enrolling consecutive patients between 1994 and 2022. Nutrition status was assessed using admission body mass index (BMI), albumin, total bilirubin, cholesterol, c-reactive protein, hemoglobin a1c, high-density lipoprotein, hemoglobin, low-density lipoprotein, mean corpuscular volume, alanine transaminase, and triglycerides. Main outcome was favorable discharge outcome (mRS 0\u20132). Multivariable logistic regression was conducted with adjustment for baseline differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 2170 patients, 1152 had deep and 1018 had lobar ICH. Overweight BMI was associated with higher odds of favorable discharge outcome in all (aOR\u2009=\u20093.01, 95% CI 1.59\u20135.69, p\u2009=\u20090.001) and lobar (aOR\u2009=\u20093.26, 95% CI 1.32\u20138.08, p\u2009=\u20090.011) ICH after adjustment for baseline differences. This association did not reach statistical significance in deep (aOR\u2009=\u20092.77, 95% CI 0.99\u20137.72, p\u2009=\u20090.052) ICH. No lab values were associated with functional outcome in all, deep, or lobar ICH after adjustment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and Conclusion:<\/jats:title>\n                    <jats:p>Overweight BMI was associated with favorable discharge status after ICH. These findings could inform future studies to determine whether overweight BMI has a protective effect in ICH patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23969873241253048","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T08:58:39Z","timestamp":1715590719000},"page":"1074-1082","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Nutrition markers and discharge outcome in deep and lobar intracerebral hemorrhage"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1771-6710","authenticated-orcid":false,"given":"Jonathan","family":"Duskin","sequence":"first","affiliation":[{"name":"Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA 1"},{"name":"Department of Neurology, Massachusetts General Hospital, Boston, MA, USA 2"},{"name":"Broad Institute of MIT and Harvard, 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