{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T17:47:46Z","timestamp":1783360066043,"version":"3.54.6"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"vor","delay-in-days":103,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There are limited therapeutic options in cases of failed reperfusion (modified thrombolysis in cerebral infarction [mTICI] score\u2009&amp;lt;\u20092b) after stent-retriever and\/or aspiration based endovascular treatment (EVT) for acute ischemic stroke. Despite the absence of data supporting its use, rescue therapy (balloon angioplasty and\/or stent implantation) is often utilized in such cases. Studies are limited to large vessel occlusions, while the outcomes and complications after rescue therapy in medium\/distal vessel occlusions (MDVOs) have not been reported. This study aims to report the outcomes of rescue therapy in MDVO stroke patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed an analysis of the \u201cBlood pressure and Antiplatelet medication management after reScue angioplasty after failed Endovascular treatment in Large and distal vessel occlusions with probable IntraCranial Atherosclerotic Disease\u201d (BASEL ICAD) retrospective registry. All MDVO stroke patients were included in the analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Out of the 718 registry patients, 87 (12.1%) presented with an MDVO. Fifty-six patients (64.4%) showed an occlusion of the M2 segment of the middle cerebral artery. Rescue stenting was performed in 78 patients (89.7%) while balloon angioplasty alone was performed in 9 patients (10.3%). Successful reperfusion (mTICI score\u2009\u2a7e\u20092b) was achieved in 73 (83.9%) patients after rescue therapy. Symptomatic intracranial hemorrhage (sICH) occurred in 8 patients (9.2%) and post-treatment stent occlusion in 12 patients (13.8%). Ninety\u2009days mortality was 20.7%. Twenty-eight patients (32.2%) achieved functional independence at 90\u2009days (modified Rankin Scale 0\u20132).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Rescue therapy with stenting and\/or balloon angioplasty in patients undergoing EVT for isolated MDVO with suspected underlying intracranial atherosclerotic disease is an effective reperfusion strategy but is associated with complications and poor functional outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23969873241311152","type":"journal-article","created":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T07:59:07Z","timestamp":1735977547000},"page":"713-720","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Rescue therapy after failed thrombectomy in medium\/distal vessel occlusions: A retrospective analysis of an international, multi-center registry"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5405-4237","authenticated-orcid":false,"given":"Aikaterini","family":"Anastasiou","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, University Hospital Basel, Basel, Switzerland 1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1630-6210","authenticated-orcid":false,"given":"Alex","family":"Brehm","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Basel, Basel, Switzerland 1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Dobrocky","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Inselspital University Hospital Bern, University of Bern, Bern, Switzerland 2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6839-7134","authenticated-orcid":false,"given":"Adnan","family":"Mujanovic","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Inselspital University Hospital Bern, University of Bern, Bern, Switzerland 2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"de Dios Lascuevas","sequence":"additional","affiliation":[{"name":"Interventional Neuroradiology, Vall d\u2019Hebron University Hospital, Barcelona, Spain 3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Carmona Fuentes","sequence":"additional","affiliation":[{"name":"Interventional Neuroradiology, Vall d\u2019Hebron University Hospital, Barcelona, Spain 3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"L\u00f3pez-Fr\u00edas L\u00f3pez-Jurado","sequence":"additional","affiliation":[{"name":"Interventional Neuroradiology, Hospital Cl\u00ednico San Carlos, Madrid, Spain 4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blanca","family":"Hidalgo Valverde","sequence":"additional","affiliation":[{"name":"Stroke Unit, Department of Neurology, Hospital Cl\u00ednico San Carlos, Madrid, Spain 5"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ansgar","family":"Berlis","sequence":"additional","affiliation":[{"name":"Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Augsburg, Germany 6"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph J.","family":"Maurer","sequence":"additional","affiliation":[{"name":"Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Augsburg, Germany 6"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2810-1685","authenticated-orcid":false,"given":"Thanh N","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA 7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"Abdalkader","sequence":"additional","affiliation":[{"name":"Department of Radiology, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA 7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7468-137X","authenticated-orcid":false,"given":"Piers","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Radiology, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA 7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Thevoz","sequence":"additional","affiliation":[{"name":"Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital, Lausanne, Switzerland 8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrik","family":"Michel","sequence":"additional","affiliation":[{"name":"Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital, Lausanne, Switzerland 8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius","family":"Kaschner","sequence":"additional","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional Radiology, University Duesseldorf, D\u00fcsseldorf, Germany 9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Weiss","sequence":"additional","affiliation":[{"name":"Medical Faculty, Department of Diagnostic and Interventional 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