{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T03:58:43Z","timestamp":1787630323951,"version":"build-2736575974"},"reference-count":20,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T00:00:00Z","timestamp":1740355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Scleroderma and Related Disorders"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Interstitial lung disease in systemic sclerosis has a significant impact in the quality of life. This prospective study was designed to determine the correlation between quality of life in systemic sclerosis-interstitial lung disease patients using patient-reported outcome measures and the lung function test parameters, with assessment done at baseline and 1\u2009year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In total, 63 consecutive systemic sclerosis-interstitial lung disease patients underwent lung function test, 6-minute walk distance, and quality of life\u2013validated questionnaires (King\u2019s Brief Interstitial Lung Disease and Functional Assessment of Chronic Illness Therapy dyspnea). King\u2019s Brief Interstitial Lung Disease covers three components, namely chest, breathlessness, and psychological symptoms. The Functional Assessment of Chronic Illness Therapy dyspnea score has Part I (breathlessness symptoms) and Part II (physical limitation due to breathlessness). All assessments except for 6-minute walk distance were done both at baseline and at 12\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Both forced vital capacity predicted percentage at baseline and 12\u2009months had significant negative correlation with the Functional Assessment of Chronic Illness Therapy dyspnea score Part I (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      values: 0.038 and &lt;0.001, respectively). Both forced vital capacity and diffuse capacity for carbon monoxide predicted percentage at 12\u2009months were also negatively correlated with Functional Assessment of Chronic Illness Therapy dyspnea score Part II (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      values: 0.001 and 0.010, respectively). There was no significant correlation between King\u2019s Brief Interstitial Lung Disease score and the lung function parameters, at both baseline and at 1-year interval. Positive significant correlation was observed between forced vital capacity predicted percentage at baseline and 6-minute walk distance (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Systemic sclerosis-interstitial lung disease affects quality of life, which is best assessed using the Functional Assessment of Chronic Illness Therapy dyspnea score as it correlates significantly with the lung function test parameters.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23971983251318827","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T06:48:03Z","timestamp":1740379683000},"page":"395-402","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Quality of life in scleroderma-related interstitial lung disease and its association with respiratory clinical parameters"],"prefix":"10.1136","volume":"10","author":[{"given":"Thayalan","family":"Ponniah","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Department of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee Kuan","family":"Wong","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choung Min","family":"Ng","sequence":"additional","affiliation":[{"name":"Institute of Mathematical Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3347-1362","authenticated-orcid":false,"given":"Jasmin","family":"Raja","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,2,24]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2018.08.005"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1903076"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel221"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2020-000598"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20591"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.07.012"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2012-201581"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa827"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.4102\/sajp.v77i1.1549"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01913-2018"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/23971983211013979"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201903-0563CI"},{"issue":"2","key":"e_1_3_2_14_2","first-page":"152","article-title":"The assessment of health-related quality of life in scleroderma-interstitial lung disease","volume":"2","author":"Lari MS","year":"2014","unstructured":"Lari MS, Mirfaeizi SZ, Shariati Z, et al. The assessment of health-related quality of life in scleroderma-interstitial lung disease. J Cardiothorac Med 2014; 2(2): 152\u2013157.","journal-title":"J Cardiothorac Med"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00145-2020"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2020-217455"},{"issue":"4","key":"e_1_3_2_17_2","first-page":"161","article-title":"Usefulness of six-minute walk test in systemic sclerosis","volume":"113","author":"Rizzi M","year":"2018","unstructured":"Rizzi M, Radovanovic D, Santus P, et al. Usefulness of six-minute walk test in systemic sclerosis. Clin Exp Rheumatol 2018; 36 Suppl. 113(4): 161\u2013167.","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.30467"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.38390"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keac576"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kez486"}],"container-title":["Journal of Scleroderma and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23971983251318827","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/23971983251318827","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23971983251318827","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T11:53:05Z","timestamp":1777981985000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/23971983251318827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,24]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1177\/23971983251318827"],"URL":"https:\/\/doi.org\/10.1177\/23971983251318827","relation":{},"ISSN":["2397-1983","2397-1991"],"issn-type":[{"value":"2397-1983","type":"print"},{"value":"2397-1991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,24]]}}}