{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T04:40:20Z","timestamp":1778647220637,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T00:00:00Z","timestamp":1632873600000},"content-version":"vor","delay-in-days":90,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the oncologic and functional outcomes of transoral laser microsurgery (TLM) for glottic cancers in patients \u226580 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospectively collected case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>QEII Health Sciences Centre, Halifax, Canada.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This case series used a prospectively collected glottic cancer database to examine consecutive elderly patients (\u226580 years old) undergoing TLM. Kaplan\u2010Meier analysis was used to evaluate rates of disease\u2010free, disease\u2010specific, and overall survival as the primary end points of oncologic control. Secondary functional outcomes included voice function, length of hospital stay, and time to readmission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2005 to 2017, 17 octogenarian patients underwent TLM for glottic cancer. Median follow\u2010up was 4.19 years (interquartile range, 0.71\u20106.95). Kaplan\u2010Meier estimates of 5\u2010year survival were 78.4% (disease free), 92.9% (disease specific), and 81.9% (overall). The median length of hospital stay was 1\u00a0day (range, 0\u20108). There was only 1 readmission within 30\u00a0days of surgery. No patients in this study developed significant surgical or postoperative complications requiring unplanned readmissions. Patient\u2010perceived voice function improved to normal after treatment in 62.5% of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this study suggest that TLM is a safe and effective treatment modality for glottic cancer in patients aged \u226580 years, providing good oncologic control and satisfactory functional outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1177\/2473974x211046957","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T11:52:30Z","timestamp":1632916350000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Functional and Oncologic Outcomes of Octogenarians Undergoing Transoral Laser Microsurgery for Laryngeal Cancer"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0862-6684","authenticated-orcid":false,"given":"Changseok","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Queen Elizabeth II Health Sciences Center and Dalhousie University Halifax Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Forner","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Queen Elizabeth II Health Sciences Center and Dalhousie University Halifax Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher W.","family":"Noel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Toronto Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Taylor","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Queen Elizabeth II Health Sciences Center and Dalhousie University Halifax Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"MacKay","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Queen Elizabeth II Health Sciences Center and Dalhousie University Halifax Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew H.","family":"Rigby","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Queen Elizabeth II Health Sciences Center and Dalhousie University Halifax Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Corsten","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Queen Elizabeth II Health Sciences Center and Dalhousie University Halifax Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan R.","family":"Trites","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Queen Elizabeth II Health Sciences Center and Dalhousie University Halifax Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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