{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:08:07Z","timestamp":1791644887176,"version":"4.3.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>We report a presumptive case of bilateral placoid choroiditis secondary to disseminated Cryptococcus neoformans infection and review the literature on choroidal involvement of C neoformans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A case report is presented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A 35-year-old HIV-positive man presented with disseminated cryptococcal infection. Cryptococcal meningitis was confirmed by lumbar puncture, and skin involvement was confirmed by microscopy of scrapings from a papular, umbilicated, ulcerated lesion. Ophthalmologic examination revealed intact visual acuity, clear vitreous, and multiple yellowish, placoid-appearing choroidal lesions in the posterior pole bilaterally.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Multifocal choroiditis caused by C neoformans is an uncommon manifestation of disseminated infection, and placoid yellowish choroidal lesions are an unusual variant. These findings must be differentiated from choroidal tuberculosis and other infections. Multifocal choroiditis typically occurs in AIDS patients and may precede the presentation of meningitis. In such patients, choroidal lesions warrant investigation for systemic, life-threatening opportunistic infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2474126420936191","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T06:53:18Z","timestamp":1595314398000},"page":"530-533","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Bilateral Placoid Choroiditis in an HIV-Positive Patient With\n                    <i>Cryptococcus neoformans<\/i>\n                    Meningitis and Disseminated                     Cryptococcal Disease"],"prefix":"10.1177","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2218-984X","authenticated-orcid":false,"given":"Ryan D.","family":"Larochelle","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Colorado, Denver, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marissa B.","family":"Larochelle","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, University of Utah,\r                Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee Yee","family":"Aung","sequence":"additional","affiliation":[{"name":"Medical Action Myanmar, Yangon, Myanmar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thinzar","family":"Linn","sequence":"additional","affiliation":[{"name":"Medical Action Myanmar, Yangon, Myanmar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Heiden","sequence":"additional","affiliation":[{"name":"Pacific Eye Associates, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert T.","family":"Vitale","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, University of Utah,\r                Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,7,21]]},"reference":[{"key":"bibr1-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30243-8"},{"key":"bibr2-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)73472-5"},{"key":"bibr3-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1080\/09273940802204568"},{"key":"bibr4-2474126420936191","first-page":"623","volume":"93","author":"Jabs DA","year":"1995","journal-title":"Trans Am Ophthalmol Soc"},{"key":"bibr5-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(89)90303-6"},{"key":"bibr6-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005810624388"},{"key":"bibr7-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(93)31543-5"},{"key":"bibr8-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1016\/j.optm.2006.06.005"},{"key":"bibr9-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(89)90660-0"},{"key":"bibr10-2474126420936191","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00269-8"}],"container-title":["Journal of VitreoRetinal Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2474126420936191","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2474126420936191","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2474126420936191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:25:19Z","timestamp":1790695519000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2474126420936191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,21]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1177\/2474126420936191"],"URL":"https:\/\/doi.org\/10.1177\/2474126420936191","relation":{},"ISSN":["2474-1264","2474-1272"],"issn-type":[{"value":"2474-1264","type":"print"},{"value":"2474-1272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,21]]}}}