{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:05:33Z","timestamp":1790697933872,"version":"4.1.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T00:00:00Z","timestamp":1606262400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>We describe subtle macular changes that were detected by high-magnification color fundus imaging in infants with congenital Zika syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This series included 4 infants (age: 1.4 \u00b1 0.1 years [range, 1.3-1.5 years]) who were serologically confirmed with congenital Zika syndrome, examined under anesthesia, and underwent fundus examination and color fundus documentation. The fundus images were captured using 130\u00b0 and 80\u00b0 field lenses. Fluorescein angiography confirmed macular lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Wide-angle color fundus images detected unilateral retinal findings in all 4 infants. Chorioretinal atrophy was identified in 2 eyes (25%) of 2 infants (50%) and pigment mottling in 3 eyes (37.5%) of 2 infants (50%). High-magnification imaging revealed subtle macular changes in the contralateral eyes of the 4 infants that were confirmed by fluorescein angiography imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>High-magnification fundus imaging can be effective and reliable in revealing and documenting subtle structural changes in the macula of infants with congenital Zika syndrome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2474126420972256","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T03:53:57Z","timestamp":1606276437000},"page":"425-430","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Color Fundus Imaging Using a High-Magnification Lens for Detecting Subtle Macular Changes in Infants With Congenital Zika Syndrome"],"prefix":"10.1177","volume":"5","author":[{"given":"Camila V.","family":"Ventura","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Altino Ventura Foundation, Recife, Brazil"},{"name":"Department of Ophthalmology, HOPE Eye Hospital, Recife, Brazil"},{"name":"Department of Research, Altino Ventura Foundation, Recife, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itamara","family":"Arag\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Altino Ventura Foundation, Recife, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liana O.","family":"Ventura","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Altino Ventura Foundation, Recife, Brazil"},{"name":"Department of Ophthalmology, HOPE Eye Hospital, Recife, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,11,25]]},"reference":[{"key":"bibr1-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00006-4"},{"key":"bibr2-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2016.0267"},{"key":"bibr3-2474126420972256","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20160002"},{"key":"bibr4-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2016.1784"},{"key":"bibr5-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2017.0561"},{"key":"bibr6-2474126420972256","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20180907-14"},{"key":"bibr7-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2017.1474"},{"key":"bibr8-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2017.05.024"},{"key":"bibr9-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2016.10.004"},{"key":"bibr10-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.06.009"},{"key":"bibr11-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001150"},{"key":"bibr12-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2016.05.001"},{"key":"bibr13-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2012.02557.x"},{"key":"bibr14-2474126420972256","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20130528-04"},{"key":"bibr15-2474126420972256","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-009-1077-7"},{"key":"bibr16-2474126420972256","unstructured":"Natus Medical Inc. Because every newborn deserves clear vision. RetCam3, 2019. 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