{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:04:42Z","timestamp":1790697882599,"version":"4.1.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,10,24]],"date-time":"2021-10-24T00:00:00Z","timestamp":1635033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100005242","name":"Heed Ophthalmic Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005242","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Ocular syphilis can present as a wide variety of clinical phenotypes, among them panuveitis with vasculitis. Primary retinal phlebitis with resulting paravenous atrophy and pigmentary retinal degeneration is a rare presentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A 53-year-old man presented with a 1-year history of bilateral blurry vision. Physical examination demonstrated bilateral anterior chamber and vitreous cell with vitreous haze, hyperemic optic nerves, and atrophic-appearing retina. The left eye demonstrated a nasal area of perivenular vascular sheathing with adjacent retinal whitening. Ancillary testing demonstrated predominantly perivenular leakage involvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Uveitic workup was positive for syphilis and HIV. The patient was treated with antiretroviral therapy and intravenous penicillin G. He developed progressive paravenous pigmentary changes and atrophy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Syphilis can present with a wide variety of phenotypic manifestations and should also be considered in patients presenting with acute retinal phlebitis or paravenous atrophy in long-standing cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/24741264211046772","type":"journal-article","created":{"date-parts":[[2021,10,24]],"date-time":"2021-10-24T23:46:36Z","timestamp":1635119196000},"page":"474-478","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Ocular Syphilis With Phlebitis and Paravenous Pigmentary Retinopathy"],"prefix":"10.1177","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7496-5118","authenticated-orcid":false,"given":"Danny A.","family":"Mammo","sequence":"first","affiliation":[{"name":"Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Careen Y.","family":"Lowder","sequence":"additional","affiliation":[{"name":"Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil K.","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,24]]},"reference":[{"key":"bibr1-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.133843"},{"key":"bibr2-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-199010030-00012"},{"key":"bibr3-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-198400440-00003"},{"issue":"7","key":"bibr4-24741264211046772","first-page":"825","volume":"13","author":"Lobes LA","year":"1981","journal-title":"Ann Ophthalmol"},{"key":"bibr5-24741264211046772","author":"Li KH","journal-title":"Ocul Immunol Inflamm"},{"key":"bibr6-24741264211046772","author":"Vidal-Villegas B","journal-title":"Ocul Immunol Inflamm"},{"key":"bibr7-24741264211046772","doi-asserted-by":"publisher","DOI":"10.3109\/09273948.2013.841960"},{"key":"bibr8-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1177\/2474126420936586"},{"key":"bibr9-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1186\/s12348-015-0056-x"},{"key":"bibr10-24741264211046772","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2014.1648"},{"key":"bibr11-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(48)91817-0"},{"key":"bibr12-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.59"},{"key":"bibr13-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1996.182"},{"key":"bibr14-24741264211046772","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199707313370504"}],"container-title":["Journal of VitreoRetinal Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24741264211046772","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/24741264211046772","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24741264211046772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:25:32Z","timestamp":1790695532000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/24741264211046772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,24]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1177\/24741264211046772"],"URL":"https:\/\/doi.org\/10.1177\/24741264211046772","relation":{},"ISSN":["2474-1264","2474-1272"],"issn-type":[{"value":"2474-1264","type":"print"},{"value":"2474-1272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,24]]}}}