{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:05:18Z","timestamp":1790697918551,"version":"4.1.0"},"reference-count":41,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,2,18]],"date-time":"2024-02-18T00:00:00Z","timestamp":1708214400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>Purpose: To describe the first use of high-dose-rate yttrium-90 disc brachytherapy for choroidal melanoma. Methods: A 72-year-old patient had a cT1-category choroidal melanoma characterized by the presence of orange pigment, increasing subretinal fluid (SRF), and enlarging tumor thickness. It was treated with single-session, light-guided, light-defined yttrium-90-disc brachytherapy. Results: A specialized handheld applicator provided with 4 encircling lights was used to guide plaque placement and localize treatment. Unlike low-dose-rate plaques, high-dose-rate yttrium-90 required only 3 minutes 39 seconds. In this case, treatment did not require episcleral sutures, muscle relocation, outpatient dwell time, or a second surgery. High-dose-rate treatment improved radiation safety by eliminating perioperative exposure to health care personnel, the community, and the family. At the 13-month follow-up, the SRF and tumor thickness were diminished. There was no secondary cataract, radiation retinopathy, maculopathy, or optic neuropathy, and the visual acuity was 20\/20. Conclusions: Yttrium-90 brachytherapy allowed for single-surgery, minimally invasive, outpatient irradiation of a choroidal melanoma.<\/jats:p>","DOI":"10.1177\/24741264241227684","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:16:38Z","timestamp":1708301798000},"page":"210-214","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Yttrium-90 Episcleral Plaque Brachytherapy for Choroidal Melanoma"],"prefix":"10.1177","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8111-3896","authenticated-orcid":false,"given":"Paul T.","family":"Finger","sequence":"first","affiliation":[{"name":"The New York Eye Cancer Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,18]]},"reference":[{"key":"bibr1-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1016\/j.brachy.2013.11.008"},{"key":"bibr2-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1118\/1.4749933"},{"key":"bibr3-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-18757-6_14"},{"key":"bibr4-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1991.01080110148053"},{"key":"bibr5-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.12.027"},{"key":"bibr6-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.70.11.844"},{"key":"bibr7-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1051007"},{"key":"bibr8-24741264241227684","doi-asserted-by":"publisher","DOI":"10.5114\/jcb.2021.106191"},{"key":"bibr9-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.068460"},{"key":"bibr10-24741264241227684","doi-asserted-by":"publisher","DOI":"10.17116\/oftalma201513125-11"},{"key":"bibr11-24741264241227684","doi-asserted-by":"publisher","DOI":"10.1007\/s004170050059"},{"key":"bibr12-24741264241227684","first-page":"469","volume":"50","author":"Hughes WF","year":"1952","journal-title":"Trans Am Ophthalmol Soc"},{"key":"bibr13-24741264241227684","unstructured":"U.S. Food & Drug Administration. 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