{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:13:42Z","timestamp":1791764022786,"version":"4.3.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Foundation Fighting Blindness","award":["CD-C-0918-0748-EEC"],"award-info":[{"award-number":["CD-C-0918-0748-EEC"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Purpose: To describe a case of pentosan polysulfate maculopathy progression with 13 years of follow-up imaging. Methods: A case was analyzed and a literature review performed. Results: A 65-year-old woman was referred to the retina service for a second opinion of a bilateral progressive pigmentary maculopathy. Her medical history was significant for interstitial cystitis that was actively treated with daily pentosan polysulfate since 2003. Multimodal imaging and fundus examination were consistent with pentosan polysulfate maculopathy. A review of records showed previous fundus imaging dating back 13 years that permitted longitudinal assessment of the disease course. Imaging findings were more prominent than the fundus examination findings. There was a 5-year period from the onset of parafoveal atrophy to foveal involvement. A pseudopodial pattern of disease expansion was seen on fundus autofluorescence. Conclusions: To our knowledge, this case represents the longest documented follow-up imaging of the progression of pentosan polysulfate maculopathy in the literature.<\/jats:p>","DOI":"10.1177\/24741264241228375","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T04:49:40Z","timestamp":1706676580000},"page":"325-333","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Pentosan Polysulfate Maculopathy With 13 Years of Follow-up Imaging"],"prefix":"10.1177","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4329-0733","authenticated-orcid":false,"given":"Ashlyn M.","family":"Pinto","sequence":"first","affiliation":[{"name":"Department of Ophthalmology & Visual Sciences, Dalhousie University, Halifax, NS, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nieraj","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Rishi","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology & Visual Sciences, Dalhousie University, Halifax, NS, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,1,31]]},"reference":[{"key":"bibr1-24741264241228375","unstructured":"Lim Y, O\u2019Rourke S. Interstitial cystitis. In: StatPearls. StatPearls Publishing; 2022. Accessed December 11, 2022. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK570588\/"},{"key":"bibr2-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2021.05.005"},{"key":"bibr3-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2018.02.011"},{"key":"bibr4-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.04.026"},{"key":"bibr5-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2020.01.017"},{"key":"bibr6-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2019.10.013"},{"key":"bibr7-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2020.05.008"},{"key":"bibr8-24741264241228375","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20201223-04"},{"key":"bibr9-24741264241228375","unstructured":"Janssen Pharmaceuticals, Inc. ELMIRON\n                      \u00ae\n                      [package insert]. 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Accessed December 11, 2022. https:\/\/www.canada.ca\/en\/health-canada\/services\/drugs-health-products\/medeffect-canada\/health-product-infowatch\/health-product-infowatch-october-2019.html#a3.2"},{"key":"bibr16-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2021.07.004"},{"key":"bibr17-24741264241228375","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2020.2349"}],"container-title":["Journal of VitreoRetinal Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24741264241228375","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/24741264241228375","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24741264241228375","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:26:33Z","timestamp":1790695593000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/24741264241228375"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,31]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1177\/24741264241228375"],"URL":"https:\/\/doi.org\/10.1177\/24741264241228375","relation":{},"ISSN":["2474-1264","2474-1272"],"issn-type":[{"value":"2474-1264","type":"print"},{"value":"2474-1272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,31]]}}}