{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:17:22Z","timestamp":1793420242758,"version":"4.5.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"J. Arch McNamara Memorial Fund"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>Purpose: To examine the characteristics of eyes with high-risk lattice degeneration treated with laser retinopexy and determine the indications, safety, and outcomes of the treatment. Methods: This interventional single-surgeon consecutive retrospective study was conducted at Wills Eye Hospital between 2014 and 2021. The series included eyes with lattice degeneration with high-risk lesions. Documented characteristics and outcomes of these eyes and fellow eyes were documented. Results: The study comprised 167 eyes of 143 patients (53.3% women; mean age [\u00b1SD], 50\u2009\u00b1\u200917 years). Complications after laser treatment included new posterior vitreous detachment (PVD) (n\u2009=\u200921), epiretinal membrane (ERM) (n\u2009=\u200913), retinal detachment (RD) (n\u2009=\u20095), and additional laser required (n\u2009=\u200922). Eyes that developed ERMs were more likely to develop PVDs (odds ratio, 5.39; 95% CI, 1.57-18.47). Patents who developed ERMs were older (mean, 60\u2009\u00b1\u20097 years vs 49\u2009\u00b1\u200917 years; P\u2009=\u2009.016), as were those developing PVDs (mean, 59\u2009\u00b1\u20098 years vs 48\u2009\u00b1\u200917; P\u2009=\u2009.005). No eye with a new ERM required surgery (n\u2009=\u200913). Four eyes with a new RD required laser retinopexy alone; 1 eye was treated surgically. No eye had an RD at the most recent evaluation. Conclusions: Despite high-risk lesions in areas of lattice degeneration, few eyes developed RDs after prophylactic laser retinopexy. Older patients may have a higher risk for ERM or PVD after laser treatment. Eyes with post-laser PVD were more likely to develop an ERM.<\/jats:p>","DOI":"10.1177\/24741264241248253","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T03:32:03Z","timestamp":1714015923000},"page":"381-387","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Indications and Outcomes of Laser Retinopexy in Eyes With High-Risk Lattice Degeneration"],"prefix":"10.1177","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6846-4739","authenticated-orcid":false,"given":"Adina S.","family":"Kazan","sequence":"first","affiliation":[{"name":"Thomas Jefferson University Sidney Kimmel Medical College, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5818-9083","authenticated-orcid":false,"given":"Raziyeh","family":"Mahmoudzadeh","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirataollah","family":"Salabati","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Sharpe","sequence":"additional","affiliation":[{"name":"Biostatistics Consulting Core, Vicky and Jack Farber Vision Research Center, Wills Eye Hospital, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell S.","family":"Fineman","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Hsu","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6847-7169","authenticated-orcid":false,"given":"Yoshihiro","family":"Yonekawa","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc J.","family":"Spirn","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"bibr1-24741264241248253","unstructured":"Lattice Degeneration. 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