{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:05:21Z","timestamp":1790697921679,"version":"4.1.0"},"reference-count":48,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["Career Development Award"],"award-info":[{"award-number":["Career Development Award"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008522","name":"University of Illinois at Chicago","doi-asserted-by":"publisher","award":["Unrestricted Departmental Funding"],"award-info":[{"award-number":["Unrestricted Departmental Funding"]}],"id":[{"id":"10.13039\/100008522","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K12EY27720"],"award-info":[{"award-number":["K12EY27720"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30EY10572"],"award-info":[{"award-number":["P30EY10572"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>\n                    <jats:bold>Purpose:<\/jats:bold>\n                    To study the influence of ultra-widefield fluorescein angiography (FA) on the diagnosis and management of diabetic retinopathy (DR).\n                    <jats:bold>Methods:<\/jats:bold>\n                    Ten experts in DR completed an online survey in which they were asked to diagnose and manage DR cases using different imaging modalities. Experts independently reviewed 20 cases of DR and provided a diagnosis and management plan for each case, first based on ultra-widefield color-free and red-free images alone and again with the corresponding ultra-widefield FA images. Experts were polled on their diagnostic confidence, use of FA in clinical practice, and opinions on the value of ultra-widefield FA. Based on the reference standard diagnosis, primary outcomes included diagnostic sensitivity and specificity with and without ultra-widefield FA. Secondary outcomes included intergrader agreement, expert confidence, management outcomes, and an analysis of experts\u2019 opinions on the clinical use of ultra-widefield FA.\n                    <jats:bold>Results:<\/jats:bold>\n                    Diagnostic sensitivity (95% CI) increased from 36% (29%-43%) to 69% (62%-75%) (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .05) with ultra-widefield FA. Intergrader agreement (Fleiss kappa statistic, 0.29 [95% CI, 0.21-0.27] vs 0.44 [95% CI, 0.40-0.47];\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.05) and expert confidence (38% vs 65%) also improved. In 39% of responses, management was changed from observation to treatment. Although 40% of experts did not request FA with the initial ultra-widefield color-free\/red-free images, 80% found ultra-widefield FA clinically useful when provided.\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Diagnosis, treatment, and expert opinions on the use of FA all changed when a corresponding ultra-widefield FA was available. Incorporating FA into routine clinical practice may facilitate more accurate clinical decision-making.\n                  <\/jats:p>","DOI":"10.1177\/24741264251359907","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T05:19:02Z","timestamp":1754111942000},"page":"667-677","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The Influence of Ultra-Widefield Fluorescein Angiography on the Diagnosis and Management of Diabetic Retinopathy"],"prefix":"10.1177","volume":"9","author":[{"given":"Nicole K.","family":"Scripsema","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7091-6901","authenticated-orcid":false,"given":"Tala","family":"Al-Khaled","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joelle A.","family":"Hallak","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rawan","family":"Allozi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aziz A.","family":"Khanifar","sequence":"additional","affiliation":[{"name":"The Retina Group of Washington, Greenbelt, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanos D.","family":"Papakostas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Weill Cornell Medical College, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3135-1922","authenticated-orcid":false,"given":"Christina Y.","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald C.","family":"Gentile","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye &amp; Ear Infirmary of Mount Sinai, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Peter","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Casey Eye Institute, Oregon Health &amp; Science University, Portland, OR, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica G.","family":"Lee","sequence":"additional","affiliation":[{"name":"Long Island and Queens Vitreoretinal Consultants, Northwell Health Eye Institute, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennady","family":"Landa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye &amp; Ear Infirmary of Mount Sinai, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix Y.","family":"Chau","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F.","family":"Mieler","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meenakashi","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye &amp; Ear Infirmary of Mount Sinai, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amani A.","family":"Fawzi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy E.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer I.","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1971-2249","authenticated-orcid":false,"given":"Robison Vernon Paul","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1005073"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0161-6420(78)35693-1"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(13)38011-7"},{"key":"e_1_3_2_5_2","first-page":"786","article-title":"ETDRS report number 10. 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