{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:03:30Z","timestamp":1790697810886,"version":"4.1.0"},"reference-count":11,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"\n Purpose:<\/jats:bold>\n To describe a novel surgical approach for eyes with persistent macular edema (ME) complicated by intracystic hyperreflective material.\n Methods:<\/jats:bold>\n Pars plana vitrectomy and dye-assisted internal limiting membrane (ILM) peeling were performed in cases with chronic and\/or refractory intracystic hyperreflective material. Microscope-integrated optical coherence tomography (OCT) was used to localize cysts and intracystic hyperreflective material, perform cyst puncture, and monitor cyst collapse. Functional and structural outcomes were assessed longitudinally over a minimum follow-up of 3 months.\n Results:<\/jats:bold>\n Decimal visual acuity improved from a median of 0.28 (20\/71.4) to 0.50 (20\/40) over a median follow-up of 6 months. No patient required repeat intravitreal injection or experienced recurrence of intracystic hyperreflective material.\n Conclusions:<\/jats:bold>\n ILM peeling combined with integrated OCT-guided cyst puncture may improve outcomes and reduce treatment burden in eyes with persistent ME and intracystic hyperreflective material. Additional controlled studies are needed to establish the broader utility of this technique.\n <\/jats:p>","DOI":"10.1177\/24741264251383408","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T11:35:33Z","timestamp":1761910533000},"page":"139-144","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Structural and Functional Improvement in Persistent Macular Edema Following Internal Limiting Membrane Peeling Coupled With Integrated Optical Coherence Tomography\u2013Guided Cyst Puncture of Intracystic Hyperreflective Material"],"prefix":"10.1177","volume":"10","author":[{"given":"Abhishek","family":"Upadhyaya","sequence":"first","affiliation":[{"name":"Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritesh","family":"Narula","sequence":"additional","affiliation":[{"name":"Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, India"},{"name":"LVPEI Image Learning and Analysis Centre (LILAC), LV Prasad Eye Institute, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5779-7645","authenticated-orcid":false,"given":"Brijesh","family":"Takkar","sequence":"additional","affiliation":[{"name":"Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, India"},{"name":"Indian Health Outcomes Public Health and Health Economics (IHOPE) Research Centre, LV Prasad Eye Institute, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-021-05083-6"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20200603-02"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.2021-0462"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-017-0761-6"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.18240\/ijo.2020.11.12"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000002976"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.2174\/1874364101711010005"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-022-05774-8"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0b013e31828eef49"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S241796"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.4103\/IJO.IJO_2563_23"}],"container-title":["Journal of VitreoRetinal Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24741264251383408","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/24741264251383408","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24741264251383408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:24:23Z","timestamp":1790695463000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/24741264251383408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/24741264251383408"],"URL":"https:\/\/doi.org\/10.1177\/24741264251383408","relation":{},"ISSN":["2474-1264","2474-1272"],"issn-type":[{"value":"2474-1264","type":"print"},{"value":"2474-1272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,31]]}}}