{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T15:42:33Z","timestamp":1794238953365,"version":"4.9.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of VitreoRetinal Diseases"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:p>\n                    <jats:bold>Purpose:<\/jats:bold>\n                    To identify distinguishing optical coherence tomography (OCT) characteristics of epiretinal membranes (ERMs) secondary to retinal detachment compared with idiopathic ERMs.\n                    <jats:bold>Methods:<\/jats:bold>\n                    This retrospective study analyzed 2 cohorts treated at a tertiary referral center: ERM following rhegmatogenous retinal detachment (RRD) and idiopathic ERM. Only patients who underwent pars plana vitrectomy with membrane peeling were included. Preoperative OCT images were reviewed and graded.\n                    <jats:bold>Results:<\/jats:bold>\n                    Postoperative best-corrected visual acuity improved in both groups. In the post-RRD ERM cohort, visual acuity improved from 0.71 to 0.64 (Snellen equivalents, approximately 20\/100 to 20\/80), while in the idiopathic ERM cohort, it improved from 0.44 to 0.32 (approximately 20\/60 to 20\/40). Post-RRD ERMs were of higher stage, with 80% classified as stage 3 or 4 compared with 61% in the idiopathic group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .048). Disorganization of the retinal inner layers was more prevalent in post-RRD ERM, with 42% demonstrating grade 3 or 4 compared with 15% in idiopathic ERM (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .02). Foveal herniation was observed in 40% of post-RRD ERMs compared with 14% of idiopathic ERMs (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .009). A gap between the ERM and the retinal surface was more frequently identified in idiopathic ERM (62%) than in post-RRD ERM (17%) (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .001).\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    ERMs following RRD exhibit more severe OCT characteristics, including higher staging, increased prevalence of foveal herniation, and lower incidence of a gap between the ERM and the retinal surface. The presence of these OCT characteristics should raise suspicion for prior retinal tear or retinal detachment and may indicate a worse visual prognosis and increased surgical complexity.\n                  <\/jats:p>","DOI":"10.1177\/24741264261447505","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T06:43:33Z","timestamp":1779777813000},"page":"1155-1160","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Optical Coherence Tomography Biomarkers Differentiate Epiretinal Membranes Secondary to Retinal Detachment from Idiopathic Epiretinal Membranes"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2829-2749","authenticated-orcid":false,"given":"Sonya","family":"Besagar","sequence":"first","affiliation":[{"name":"Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7631-161X","authenticated-orcid":false,"given":"Shravika","family":"Lam","sequence":"additional","affiliation":[{"name":"Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Zhang","sequence":"additional","affiliation":[{"name":"Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Steinkerchner","sequence":"additional","affiliation":[{"name":"Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6717-6279","authenticated-orcid":false,"given":"Russel H.","family":"Dinh","sequence":"additional","affiliation":[{"name":"Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avni P.","family":"Finn","sequence":"additional","affiliation":[{"name":"Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.08.009"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702786"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0161-6420(97)30190-0"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20220032"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.18240\/ijo.2023.07.16"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(77)90317-8"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2018.1542006"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","unstructured":"Lee IJ Benjamin JE Ghorayeb GR. 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