{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:13:14Z","timestamp":1790097194407,"version":"4.0.1"},"reference-count":51,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psoriasis and Psoriatic Arthritis"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Psoriasis is a chronic inflammatory condition with cutaneous and systemic involvement. Although many efficacious treatment options are available, concerns regarding costs and duration of treatment have expanded interest in the role of integrative medical therapies for psoriasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>In this review, we aim to provide evidence for the use of integrative medical approaches in the management of psoriasis, namely approaches utilizing the microbiome, probiotics, diet, and mindfulness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed\/Medline and Google Scholar databases were searched from inception up to 16 August 2023 to identify clinical studies that evaluated how integrative medical therapies affect psoriasis severity. Search terms combined \u201cpsoriasis\u201d or \u201cpsoriatic arthritis\u201d with terms related to the microbiome, diet, and lifestyle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Multiple clinical studies have shown that integrative approaches can reduce psoriasis severity. Probiotic supplementation in psoriatic patients decreased PASI scores, decreased inflammatory markers, increased quality of life, and reduced the risk of disease relapse. Intermittent fasting, in the context of Ramadan, decreased PASI scores and plasma CRP levels. Low-calorie diets and low-calorie ketogenic diets have been shown to reduce psoriasis severity. Notably, combining low-calorie diets with biologics and cyclosporine synergistically improved psoriasis to a greater extent than pharmaceutical therapy alone. A gluten-free diet improved psoriasis and reduced antigliadin antibodies in those with hypersensitivity. Mindfulness therapies also improved psoriasis severity with and without phototherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Several studies show that integrative medicine can be used to manage psoriasis. Specifically, probiotic supplementation, diets that promote weight loss or modulate antigliadin antibodies, and mindfulness therapies may improve disease severity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/24755303241236386","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T23:02:11Z","timestamp":1708470131000},"page":"108-114","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Review of Integrative Medical Therapies for Psoriasis: The Microbiome, Probiotics, Diet, and Mindfulness"],"prefix":"10.1177","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6201-7401","authenticated-orcid":false,"given":"Mildred","family":"Min","sequence":"first","affiliation":[{"name":"Integrative Skin Science and Research, Sacramento, CA, USA"},{"name":"College of Medicine, California Northstate University, Elk Grove, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay S.","family":"Dulai","sequence":"additional","affiliation":[{"name":"Integrative Skin Science and Research, Sacramento, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2780-1022","authenticated-orcid":false,"given":"Nabeel","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Integrative Skin Science and Research, Sacramento, CA, USA"},{"name":"College of Medicine, University of Houston, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja K.","family":"Sivamani","sequence":"additional","affiliation":[{"name":"Integrative Skin Science and Research, Sacramento, CA, USA"},{"name":"College of Medicine, California Northstate University, Elk Grove, CA, USA"},{"name":"Department of Dermatology, University of California-Davis, CA, USA"},{"name":"Pacific Skin Institute, Sacramento, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"issue":"5","key":"bibr1-24755303241236386","first-page":"7","volume":"24","author":"Katta R","year":"2019","journal-title":"Skin Therapy Lett"},{"issue":"4","key":"bibr2-24755303241236386","first-page":"278","volume":"63","author":"Kim WB","year":"2017","journal-title":"Can Fam Phys"},{"key":"bibr3-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.032482"},{"key":"bibr4-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1159\/000455840"},{"key":"bibr5-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2011.01261.x"},{"key":"bibr6-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21207488"},{"key":"bibr7-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.033217"},{"key":"bibr8-24755303241236386","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3386"},{"key":"bibr9-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.15632"},{"key":"bibr10-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2103629"},{"key":"bibr11-24755303241236386","doi-asserted-by":"publisher","DOI":"10.7573\/dic.212266"},{"key":"bibr12-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.16677"},{"key":"bibr13-24755303241236386","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.26893"},{"key":"bibr14-24755303241236386","volume-title":"The National Academies Collection: Reports Funded by. National Institutes of Health","author":"ComplementaryAlternative Medicine, the United States","year":"2005"},{"key":"bibr15-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1016\/j.phanu.2021.100282"},{"key":"bibr16-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1016\/j.explore.2009.06.008"},{"key":"bibr17-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00007"},{"key":"bibr18-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22083998"},{"key":"bibr19-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13786"},{"key":"bibr20-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8111715"},{"key":"bibr21-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-22125-y"},{"key":"bibr22-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw070"},{"key":"bibr23-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1002\/art.38892"},{"key":"bibr24-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2021.09.004"},{"key":"bibr25-24755303241236386","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.6237"},{"key":"bibr26-24755303241236386","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3305"},{"key":"bibr27-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00710"},{"key":"bibr28-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-30114-4"},{"key":"bibr29-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.722"},{"key":"bibr30-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1186\/s42358-022-00243-6"},{"key":"bibr31-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2014.900541"},{"key":"bibr32-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202812"},{"key":"bibr33-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26427"},{"key":"bibr34-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3390\/nu11020478"},{"key":"bibr35-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3390\/nu11030601"},{"key":"bibr36-24755303241236386","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2021.107098"},{"key":"bibr37-24755303241236386","doi-asserted-by":"publisher","DOI":"10.3390\/nu11020277"},{"key":"bibr38-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.0c00646"},{"key":"bibr39-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-014-0372-1"},{"key":"bibr40-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2021.1959500"},{"key":"bibr41-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1993.tb03329.x"},{"key":"bibr42-24755303241236386","doi-asserted-by":"publisher","DOI":"10.23736\/S1121-421X.16.02351-5"},{"key":"bibr43-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03240.x"},{"key":"bibr44-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-017-0183-4"},{"key":"bibr45-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-018-2193-0"},{"key":"bibr46-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-97793-4"},{"key":"bibr47-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2012.10720430"},{"key":"bibr48-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2014.902483"},{"key":"bibr49-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199809000-00020"},{"key":"bibr50-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2018.03.011"},{"key":"bibr51-24755303241236386","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.2972"}],"container-title":["Journal of Psoriasis and Psoriatic Arthritis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24755303241236386","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/24755303241236386","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24755303241236386","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:37:39Z","timestamp":1777509459000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/24755303241236386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,20]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1177\/24755303241236386"],"URL":"https:\/\/doi.org\/10.1177\/24755303241236386","relation":{},"ISSN":["2475-5303","2475-5311"],"issn-type":[{"value":"2475-5303","type":"print"},{"value":"2475-5311","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,20]]}}}