{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:05:43Z","timestamp":1791201943237,"version":"4.2.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psoriasis and Psoriatic Arthritis\u00ae"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>Musculoskeletal pain associated to psoriasis without the presence of psoriatic arthritis is a poor explored issue in pediatric population. The aim of this study was to compare the health-related quality of life (HRQoL) and fatigue scores of pediatric patients with psoriasis and healthy peers and estimate the impact of musculoskeletal pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The pediatric Gait Arms Legs and Spine (pGALS) questions were used to screen for musculoskeletal pain. General HRQoL was measured using the Pediatric Quality of Life Inventory 4.0 Generic Core Scales (PedsQL 4.0) and fatigue was assessed using the PedsQL-Multidimensional Fatigue Scale (PedsQL-MFS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty psoriatic patients (12.1years old; IQR 9-15) and 50 controls (12.3 years old; IQR 8.8-15.9) were evaluated. Patients with psoriasis had long disease duration of 6.9 years (IQR 3.7-9.5) and predominantly low disease activity (PASI 3.2, IQR 0.8-6; BSA 3.0, IQR 1-8), mainly treated with topical therapy. The PedsQL 4.0 total score of psoriatic patients with musculoskeletal pain was poorer than controls with pain. Fatigue by PedsQL-MFS was also worse in patients with psoriasis and pain. The risk of impaired HRQoL was 7.7 times higher in the presence of musculoskeletal pain (OR = 7.71, 95%CI 1.66-35.78); other variables such as age, sex and severity of psoriasis did not increase the risk of HRQoL impairment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Musculoskeletal pain and fatigue may provide clues for systemic impairment in pediatric psoriatic disease and calls for effective systemic treatment to reduce disease burden and accumulated damage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/24755303251327940","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T19:46:31Z","timestamp":1742240791000},"page":"84-90","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Fatigue and the Impact of Musculoskeletal Pain on Quality of Life in Pediatric Patients With Psoriasis"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6843-2035","authenticated-orcid":false,"given":"Tha\u00eds Cugler","family":"Meneghetti","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Pediatric Rheumatology Division at Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e2nia Oliveira","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pediatric Rheumatology Division at Federal University of Paran\u00e1, Curitiba, Brazil"},{"name":"Department of Pediatrics, Pediatric Dermatology Division at Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana Martins","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pediatric Rheumatolgy Division at Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Ribeirao Preto, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virg\u00ednia Paes Leme","family":"Ferriani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pediatric Rheumatolgy Division at Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Ribeirao Preto, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14864"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2017.1395800"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-011-1587-2"},{"key":"e_1_3_5_5_2","first-page":"173","article-title":"Disease burden and quality of life in psoriasis patients with and without comorbid psoriatic arthritis: results from national psoriasis foundation panel surveys","volume":"95","author":"Edson-Heredia E","year":"2015","unstructured":"Edson-Heredia E, Zhu B, Guo J, Maeda-Chubachi T, Lebwohl M. Disease burden and quality of life in psoriasis patients with and without comorbid psoriatic arthritis: results from national psoriasis foundation panel surveys. Cutis. 2015;95:173-178.","journal-title":"Cutis"},{"key":"e_1_3_5_6_2","first-page":"1273","article-title":"The impact of psoriasis on wellbeing and clinical outcomes in juvenile psoriatic arthritis","volume":"63","author":"Low JM","year":"2024","unstructured":"Low JM, Hyrich KL, Ciurtin C, et al. The impact of psoriasis on wellbeing and clinical outcomes in juvenile psoriatic arthritis. Rheumatol (United Kingdom). 2024;63:1273-1280.","journal-title":"Rheumatol (United Kingdom)"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab865"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3906"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15375"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-019-0175-0"},{"key":"e_1_3_5_11_2","first-page":"4","article-title":"The musculoskeletal impairment negatively impacts the quality of life of children and adolescents with psoriasis","volume":"60","author":"Meneghetti TC","year":"2020","unstructured":"Meneghetti TC, Padilha TMH, Azevedo VF, et al. The musculoskeletal impairment negatively impacts the quality of life of children and adolescents with psoriasis. Adv Rheumatol Advances in Rheumatology. 2020;60:4-9.","journal-title":"Adv Rheumatol Advances in Rheumatology"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1546-0096-11-44"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.033217"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.08.049"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13402"},{"key":"e_1_3_5_16_2","first-page":"394","article-title":"Measurement Comparability of Electronic and Paper Administration of Visual Analogue Scales: A Review of Published Studies","volume":"56","author":"Byrom B","year":"2022","unstructured":"Byrom B, Elash CA, Eremenco S, et al. Measurement Comparability of Electronic and Paper Administration of Visual Analogue Scales: A Review of Published Studies. Ther Innov Regul Sci Springer Science and Business Media Deutschland GmbH. 2022;56:394-404.","journal-title":"Ther Innov Regul Sci Springer Science and Business Media Deutschland GmbH"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14361"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1367\/1539-4409(2003)003<0329:TPAAPP>2.0.CO;2"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-014-3064-5"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12276"},{"key":"e_1_3_5_21_2","first-page":"308","article-title":"Quality of life of children and adolescents from sao Paulo: reliability and validity of the Brazilian version of the pediatric quality of life inventory (TM) version 4.0 generic core scales","volume":"84","author":"Klatchoian DA","year":"2008","unstructured":"Klatchoian DA, Len CA, MTRA T, et al. Quality of life of children and adolescents from sao Paulo: reliability and validity of the Brazilian version of the pediatric quality of life inventory (TM) version 4.0 generic core scales. J Pediatr (Rio J) [Internet]. 2008;84:308-315. Available from: wos:000259170300005.","journal-title":"J Pediatr (Rio J) [Internet]"},{"key":"e_1_3_5_22_2","first-page":"2494","article-title":"The PedsQL TM multidimensional fatigue scale in pediatric Rheumatology : reliability and validity","volume":"31","author":"Varni JW","year":"2004","unstructured":"Varni JW, Burwinkle TM, Szer IS. The PedsQL TM multidimensional fatigue scale in pediatric Rheumatology : reliability and validity. J Rheumatol. 2004;31:2494-2500.","journal-title":"J Rheumatol"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.161459"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-021-00580-8"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.19942"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2023.105538"},{"key":"e_1_3_5_27_2","first-page":"11","article-title":"The musculoskeletal impairment negatively impacts the quality of life of children and adolescents with psoriasis","volume":"60","author":"Meneghetti TC","year":"2020","unstructured":"Meneghetti TC, Padilha TMH, Azevedo VF, et al. The musculoskeletal impairment negatively impacts the quality of life of children and adolescents with psoriasis. Adv Rheumatol BioMed Central Ltd. 2020;60:11.","journal-title":"Adv Rheumatol BioMed Central Ltd"}],"container-title":["Journal of Psoriasis and Psoriatic Arthritis\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24755303251327940","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/24755303251327940","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/24755303251327940","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:37:51Z","timestamp":1777509471000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/24755303251327940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,17]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1177\/24755303251327940"],"URL":"https:\/\/doi.org\/10.1177\/24755303251327940","relation":{},"ISSN":["2475-5303","2475-5311"],"issn-type":[{"value":"2475-5303","type":"print"},{"value":"2475-5311","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,17]]}}}