{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:49:01Z","timestamp":1753883341445,"version":"3.41.2"},"reference-count":17,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Vaccines and Immunotherapy"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p> The authors of this article report on a case of a patient who presented to the emergency department (ED) in anaphylaxis after receiving the Moderna\u00ae COVID-19 vaccine. The patient was hypoxic, with diffuse wheezing bilaterally to auscultation, flush skin, swollen face, and the feeling of her throat closing. Anaphylaxis can have wide range of presentation, the key is recognizing the symptoms and treating early. The incidence of anaphylaxis from COVID-19 vaccine is not well documented to date. <\/jats:p>","DOI":"10.1177\/25151355211048418","type":"journal-article","created":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T10:34:45Z","timestamp":1635417285000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Anaphylaxis after Moderna COVID-19 vaccine"],"prefix":"10.1177","volume":"9","author":[{"given":"Jeremy","family":"Mayfield","sequence":"first","affiliation":[{"name":"University of Central Florida College of Medicine, Orlando, FL, USA; Osceola Regional Medical Center, Kissimmee, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumedha","family":"Bandi","sequence":"additional","affiliation":[{"name":"University of Minnesota, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7717-3864","authenticated-orcid":false,"given":"Latha","family":"Ganti","sequence":"additional","affiliation":[{"name":"University of Central Florida College of Medicine, Orlando, FL 32827-7408, USA"},{"name":"Osceola Regional Medical Center, Kissimmee, FL, USA"},{"name":"Envision Physician Services, Plantation, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Rubero","sequence":"additional","affiliation":[{"name":"University of Central Florida College of Medicine, Orlando, FL, USA"},{"name":"Osceola Regional Medical Center, Kissimmee, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,10,28]]},"reference":[{"key":"bibr1-25151355211048418","unstructured":"Understanding mRNA COVID-19 vaccines, https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/different-vaccines\/mrna.htm (2021, accessed 18 August 2021)."},{"key":"bibr2-25151355211048418","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb9983"},{"key":"bibr3-25151355211048418","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-020-0485-4"},{"key":"bibr4-25151355211048418","unstructured":"Transfection \u2013 an overview, https:\/\/www.sciencedirect.com\/topics\/neuroscience\/transfection (2021, accessed 22 August 2021)."},{"key":"bibr5-25151355211048418","unstructured":"The Advisory Committee on Immunization Practices\u2019 interim recommendation for use of Moderna COVID-19 vaccine, https:\/\/www.cdc.gov\/mmwr\/volumes\/69\/wr\/mm695152e1.htm?s_cid=mm695152e1_w (2021, accessed 18 August 2021)."},{"key":"bibr6-25151355211048418","unstructured":"Moderna COVID-19 vaccine overview and safety, https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/different-vaccines\/Moderna.html (2021, accessed 22 August 2021)."},{"key":"bibr7-25151355211048418","volume-title":"Rosen\u2019s emergency. Medicine: concepts and clinical practice","author":"Walls Ron M","year":"2019","edition":"9"},{"key":"bibr8-25151355211048418","unstructured":"Corticosteroids for the treatment of anaphylaxis, https:\/\/www.aaaai.org\/allergist-resources\/ask-the-expert\/answers\/old-ask-the-experts\/corticosteroids-anaphylaxis (2018, accessed 18 August 2021)."},{"key":"bibr9-25151355211048418","unstructured":"Corticosteroids in management of anaphylaxis; a systematic review of evidence, volume-corticosteroids-management-anaphylaxis-systematic-review-1390allasp1.pdf (eurannallergyimm.com) (2017, accessed 18 August 2021)."},{"key":"bibr10-25151355211048418","unstructured":"The Moderna COVID-19 vaccine\u2019s local reactions, systemic reactions, adverse events, and serious adverse events, https:\/\/www.cdc.gov\/vaccines\/covid-19\/info-by-product\/moderna\/reactogenicity.html (2021, accessed 18 August 2021)."},{"key":"bibr11-25151355211048418","doi-asserted-by":"crossref","unstructured":"Allergic reactions including anaphylaxis after receipt of the first dose of Moderna COVID-19 vaccine, https:\/\/www.cdc.gov\/mmwr\/volumes\/70\/wr\/mm7004e1.htm (2021, accessed 18 August 2021).","DOI":"10.15585\/mmwr.mm7004e1"},{"key":"bibr12-25151355211048418","unstructured":"ACAAI updates to guidance on risk of allergic reactions to COVID-19 vaccines, https:\/\/acaai.org\/news\/acaai-updates-guidance-risk-allergic-reactions-covid-19-vaccines (2021, accessed 18 August 2021)."},{"key":"bibr13-25151355211048418","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13874"},{"key":"bibr14-25151355211048418","unstructured":"Interim clinical considerations for Use of COVID-19 vaccines currently authorized in the United States, https:\/\/www.cdc.gov\/vaccines\/covid-19\/info-by-product\/clinical-considerations.html (2021, accessed 21 August 2021)."},{"key":"bibr15-25151355211048418","unstructured":"NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines, https:\/\/www.nih.gov\/news-events\/news-releases\/nih-begins-study-allergic-reactions-moderna-pfizer-biontech-covid-19-vaccines (2021, accessed 18 August 2021)."},{"key":"bibr16-25151355211048418","unstructured":"https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/safety\/allergic-reaction.html (2021, accessed 21 September 2021)."},{"key":"bibr17-25151355211048418","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12044"}],"container-title":["Therapeutic Advances in Vaccines and Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25151355211048418","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/25151355211048418","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25151355211048418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T18:17:36Z","timestamp":1740939456000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/25151355211048418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":17,"alternative-id":["10.1177\/25151355211048418"],"URL":"https:\/\/doi.org\/10.1177\/25151355211048418","relation":{},"ISSN":["2515-1355","2515-1363"],"issn-type":[{"type":"print","value":"2515-1355"},{"type":"electronic","value":"2515-1363"}],"subject":[],"published":{"date-parts":[[2021,1]]},"article-number":"25151355211048418"}}