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Although it was once considered a neglected disease, the incidence and mortality rates of dengue have surged over the past decade, in part due to the expanding distribution of the Aedes spp. vector facilitated by changing climatic factors. While most infections are asymptomatic or cause mild flu-like symptoms, some cases can develop into severe forms, leading to serious complications. The burden of the disease is gradually shifting from primarily affecting children, whose immune systems are immature, to increasingly impacting the older population, who typically experience waning immune responsiveness and comorbidities. With no specific treatment available, the development of a prophylactic vaccine is crucial for long-term control and prevention. School-age children are the primary target group for immunization programs of the two recently licensed dengue vaccines. However, there is limited information on the efficacy of either vaccine among the elderly or of two further immunogenic preparations currently undergoing clinical trials. This review gives an update on dengue vaccine implementation and provides recommendations for the vaccination of persons aged 60 years and above. <\/jats:p>","DOI":"10.1177\/25151355251321718","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T09:16:11Z","timestamp":1739783771000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Recommendations for dengue vaccine implementation in the elderly population"],"prefix":"10.1177","volume":"13","author":[{"given":"Nguyen Ngoc Truong","family":"Giang","sequence":"first","affiliation":[{"name":"College of Health Sciences, VinUniversity, Hanoi, Vietnam"},{"name":"Clinical Department, Institute for Global Health & Infectious Diseases, University of North Carolina Vietnam, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7342-8348","authenticated-orcid":false,"given":"Andrew W.","family":"Taylor-Robinson","sequence":"additional","affiliation":[{"name":"College of Health Sciences, VinUniversity, VinHomes Ocean Park, Gia Lam District, Hanoi 100000, Vietnam"},{"name":"Center for Global Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,17]]},"reference":[{"key":"bibr1-25151355251321718","doi-asserted-by":"publisher","DOI":"10.1139\/cjm-2020-0572"},{"key":"bibr2-25151355251321718","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000000045"},{"key":"bibr3-25151355251321718","unstructured":"World Health Organization. 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