{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:30:35Z","timestamp":1767652235037,"version":"3.48.0"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Vaccines and Immunotherapy"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Since the introduction of the SARS-CoV-2 vaccine, the incidence of complications associated with pediatric infection has markedly declined. However, there is a notable decline in vaccination coverage among younger age groups. The objective of this study was to identify the factors associated with hesitancy to receive the SARS-CoV-2 vaccine in parents of children aged 3\u201315\u2009years in a Latin American context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional, analytical study was conducted between February and May 2023. Parents of children between the ages of 3 and 15, residing in the metropolitan region of Chile, were surveyed via an online or in-person questionnaire. Univariate analysis and a multivariate logistic regression model were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Five hundred thirty-nine surveys were completed; 61.6% of parents were aged between 21 and 40\u2009years, 42.3% had completed higher education, 79.4% had paid employment, and 98.1% were fully vaccinated. Age distribution of children was 36.9% for 3\u20135\u2009years, 42.4% for 6\u201311\u2009years, and 20.8% for 12\u201315\u2009years. 87.4% was vaccinated. In the univariate analysis, vaccine hesitancy was observed in 9%, associated mainly with children 3\u20135\u2009years, fewer doses in parents\u2019 vaccination schedule, lacking risk perception and concerns about safety, and not knowing where to access pediatric vaccine formulations against COVID-19. In the multivariate analysis, the younger age, lacking risk perception, and concerns about the vaccine\u2019s effectiveness were associated with vaccine hesitancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Addressing hesitancy toward COVID-19 vaccines is of utmost importance. Educational interventions should be implemented to inform parents about the importance and effectiveness of COVID-19 vaccination in children, with special emphasis on parents of younger children, to increase vaccination coverage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/25151355251322312","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T05:42:42Z","timestamp":1741758162000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Parental hesitancy for pediatric COVID-19 vaccines in Chile"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9332-381X","authenticated-orcid":false,"given":"Daisy","family":"Cedillo","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Universidad de Chile, Gran Avenida 3100, San Miguel, Santiago de Chile 1025000, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jes\u00fas","family":"Godoy","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidad de Chile, Santiago de Chile, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Leal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Hospital de ni\u00f1os Dr. Exequiel Gonz\u00e1lez Cort\u00e9s, San Miguel, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo","family":"Villena","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidad de Chile, Santiago de Chile, Chile"},{"name":"Department of Pediatrics, Hospital de ni\u00f1os Dr. Exequiel Gonz\u00e1lez Cort\u00e9s, San Miguel, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,3,12]]},"reference":[{"key":"e_1_3_4_2_2","unstructured":"Johns Hopkins Coronavirus Resource Center. COVID-19 map https:\/\/coronavirus.jhu.edu\/map.html (2023 accessed 2 August 2022)."},{"key":"e_1_3_4_3_2","unstructured":"World Health Organization. Interim statement on COVID-19 vaccination for children https:\/\/www.who.int\/news\/item\/11-08-2022-interim-statement-on-covid-19-vaccination-for-children (2022 accessed 9 May 2023)."},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.4067\/s0034-98872024000200253"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2024.05.063"},{"key":"e_1_3_4_6_2","unstructured":"Pan American Health Organization. COVID-19 vaccination in the Americas https:\/\/ais.paho.org\/imm\/IM_DosisAdmin-Vacunacion-es.asp (accessed 9 May 2023)."},{"key":"e_1_3_4_7_2","unstructured":"Ministry of Health of Chile. Informe-SARS-Covid-2020-2021-23-02-03.pdf https:\/\/vacunas.minsal.cl\/wp-content\/uploads\/2023\/02\/Informe-SARS-Covid-2020-2021-23-02-03.pdf (2023 accessed 24 May 2024)."},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.04.036"},{"key":"e_1_3_4_9_2","unstructured":"World Health Organization. Ten threats to global health in 2019 https:\/\/www.who.int\/vietnam\/news\/feature-stories\/detail\/ten-threats-to-global-health-in-2019 (2019 accessed 2 August 2022)."},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2021.1981087"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-022-01587-9"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2022.01.061"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9121469"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9111303"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.4067\/s0716-10182022000200273"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvacx.2021.100114"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.51451\/np.v17i1.476"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1354645"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-16769-3"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(22)00320-6"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2022.02.059"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2021.1928460"},{"issue":"1","key":"e_1_3_4_23_2","article-title":"The willingness of parents to vaccinate their children younger than 12 years against COVID-19: a cross-sectional study in Malaysia","volume":"22","author":"Leh-Ching D","year":"2022","unstructured":"Leh-Ching D, Gan G-G, Chai C-S, et al. The willingness of parents to vaccinate their children younger than 12 years against COVID-19: a cross-sectional study in Malaysia. BMC Public Health 2022; 22(1): 1265.","journal-title":"BMC Public Health"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.752323"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.779720"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedhc.2021.04.005"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9101115"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.26633\/RPSP.2021.133"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40121-023-00804-2"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0261121"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10081313"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-065453"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022-058971"},{"key":"e_1_3_4_34_2","unstructured":"Department National Drug Agency. Sixth statistical report \u201cAdverse events following immunization (AEFI) associated with the administration of SARS-CoV-2 vaccines in the pediatric and adolescent population in Chile \u201d https:\/\/www.ispch.gob.cl\/wp-content\/uploads\/2023\/01\/sexto-informe-estadistico-de-pediatria-asv-kag-VVG-asv-jrs-jmr-asv-kag-asv.pdf (2023 accessed 10 March 2024)."},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-023-00848-1"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-023-04862-z"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/imr.13108"},{"key":"e_1_3_4_38_2","unstructured":"Ministry of Health of Chile. Informe-SARS-Covid-2020-2021-23-10-30.Pdf https:\/\/vacunas.minsal.cl\/wp-content\/uploads\/2023\/11\/Informe-SARS-Covid-2020-2021-23-10-30.pdf (2023 accessed 15 April 2024)."},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.4067\/s0716-10182024000200225"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2021.1925054"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2020.1775080"}],"container-title":["Therapeutic Advances in Vaccines and Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25151355251322312","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/25151355251322312","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25151355251322312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:02:35Z","timestamp":1767650555000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/25151355251322312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,12]]},"references-count":40,"alternative-id":["10.1177\/25151355251322312"],"URL":"https:\/\/doi.org\/10.1177\/25151355251322312","relation":{},"ISSN":["2515-1355","2515-1363"],"issn-type":[{"type":"print","value":"2515-1355"},{"type":"electronic","value":"2515-1363"}],"subject":[],"published":{"date-parts":[[2025,3,12]]},"article-number":"25151355251322312"}}