{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:25:23Z","timestamp":1780637123489,"version":"3.54.1"},"reference-count":41,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Linglong Yingcheng Hospital Original Foundation","award":["YCYY2023ZZ002"],"award-info":[{"award-number":["YCYY2023ZZ002"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Evid Based Complementary Altern Med"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This review synthesizes current evidence on the efficacy of acupuncture in managing chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients, focusing on its mechanisms, clinical applications, and future research directions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This narrative review synthesizes and critically appraises findings from randomized controlled trials (RCTs), meta-analyses, and preclinical studies, evaluating acupuncture's impact on pain relief, neurological function, and quality of life. Key databases were searched for studies published up to 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nineteen RCTs (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20091174) demonstrated significant improvements in CIPN symptoms with acupuncture, particularly in reducing neuropathic pain (eg, via endogenous opioid modulation) and enhancing sensory function (eg, BDNF-mediated neuroplasticity). Optimal protocols involved 2\u20133 sessions\/week for 4\u201312 weeks, targeting acupoints such as ST36 and LI4. Acupuncture outperformed pharmacotherapy (eg, duloxetine) in safety and patient-reported outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Acupuncture is a promising adjunctive therapy for CIPN, offering multimodal mechanisms and clinical benefits. Standardization of protocols and further high-quality RCTs are needed to strengthen evidence and guide integration into oncology care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2515690x251411764","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:42:42Z","timestamp":1767375762000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A Narrative Review of the Efficacy of Acupuncture in Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients"],"prefix":"10.1177","volume":"31","author":[{"given":"Li-Juan","family":"Chen","sequence":"first","affiliation":[{"name":"Qingdao Haici Hospital Affiliated to Qingdao University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Tian","family":"Ye","sequence":"additional","affiliation":[{"name":"St. Petersburg State 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