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A PubMed (National Library of Medicine) and a ScienceDirect search was conducted using the key phrases \u2018azithromycin\u2019, \u2018meibomian\u2019, \u2018blepharitis\u2019, \u2018trachoma\u2019, \u2018toxoplasmosis\u2019 from 2010 to 2017. Articles were limited to articles published in English or at least having an English abstract. There were no restrictions on age, ethnicity, or geographic locations of patients. Topical azithromycin was found effective and safe in various ocular surface infections, in meibomian gland dysfunction and in trachoma. Also, it may substitute fluoroquinolones in corneal UV cross-linking. The World Health Organization targets for trachoma elimination are being reached only after 3 years of annual mass drug administration. Oral azithromycin can participate in combination regiments for toxoplasmosis, mainly because of its very good safety profile and may play a significant role in toxoplasmosis in pregnancy. Azithromycin is one of the safest antibiotics, well tolerated, and with special pharmacokinetic properties. Also, it is characterized by a broad antimicrobial spectrum. Azithromycin is efficacious for the treatment of a lot of ocular diseases and may be included as monotherapy or in combination therapy in new treatment protocols for more ocular infections. However, more research is needed to determine this.<\/jats:p>","DOI":"10.1177\/2515841418783622","type":"journal-article","created":{"date-parts":[[2018,7,30]],"date-time":"2018-07-30T05:46:31Z","timestamp":1532929591000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["An eye for azithromycin: review of the literature"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6648-8921","authenticated-orcid":false,"given":"Kostas A.","family":"Kagkelaris","sequence":"first","affiliation":[{"name":"Department of General Pharmacology, School of Medicine, University of Patras, Patras, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga E.","family":"Makri","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, University of Patras, Patras, 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