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Given that Down syndrome has ocular manifestations from the front to the back of the eye, it is important for physicians to become familiar with these manifestations, especially given the prevalence of Down syndrome. This review aims to discuss the varied ophthalmologic manifestations of Down syndrome \u2013 including strabismus, amblyopia, nystagmus, accommodation deficits, nasolacrimal duct obstruction, keratoconus, optic nerve pathology, neoplastic disease, and retinal pathology \u2013 to facilitate better care and visual outcomes in this important patient population.<\/jats:p>","DOI":"10.1177\/25158414221101718","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T08:45:26Z","timestamp":1656578726000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Down syndrome: a review of ocular manifestations"],"prefix":"10.1177","volume":"14","author":[{"given":"Abid","family":"Haseeb","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, 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