{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:55:51Z","timestamp":1777881351638,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmol Eye Dis"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    We report an unusual, rare case of opacification of the hydrophilic acrylic intraocular lens (IOL) 23\u2009years after the initial surgery with significant visual deterioration. Opacification of the hydrophilic acrylic IOL was primarily due to the formation of folds on the surface of the lens material, and less so due to calcium phosphate deposits. Calcification opacification can be attributed to recent events, as evidenced by deposits of dicalcium phosphate dihydrate (CaHPO\n                    <jats:sub>4<\/jats:sub>\n                    2H\n                    <jats:sub>2<\/jats:sub>\n                    O) and octacalcium phosphate (Ca\n                    <jats:sub>8<\/jats:sub>\n                    H\n                    <jats:sub>2<\/jats:sub>\n                    (PO\n                    <jats:sub>4<\/jats:sub>\n                    )\n                    <jats:sub>6<\/jats:sub>\n                    5H\n                    <jats:sub>2<\/jats:sub>\n                    O), both of which are transient calcium phosphate phases, converting hydrolytically to the thermodynamically most stable hydroxyapatite (Ca\n                    <jats:sub>10<\/jats:sub>\n                    (PO\n                    <jats:sub>4<\/jats:sub>\n                    )\n                    <jats:sub>6<\/jats:sub>\n                    (OH)\n                    <jats:sub>2<\/jats:sub>\n                    ). To our knowledge, this case of hydrophilic acrylic IOL opacification is the only one that has been described so late, 23\u2009years after cataract surgery.\n                  <\/jats:p>","DOI":"10.1177\/25158414241237713","type":"journal-article","created":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T08:34:55Z","timestamp":1711355695000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A unique late-onset intraocular lens opacification 23\u2009years after implantation: a clinical and laboratory case report"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5505-8179","authenticated-orcid":false,"given":"Panos S.","family":"Gartaganis","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, 251 Hellenic Air Force General Hospital, 3 Kanellopoulou Ave., Athens 11525, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiota D.","family":"Natsi","sequence":"additional","affiliation":[{"name":"Laboratory of Inorganic and Analytical Chemistry, Department of Chemical Engineering, University of Patras and FORTH-ICEHT, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sotirios P.","family":"Gartaganis","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, University of Patras, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petros G.","family":"Koutsoukos","sequence":"additional","affiliation":[{"name":"Laboratory of Inorganic and Analytical Chemistry, Department of Chemical Engineering, University of Patras and FORTH-ICEHT, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horst","family":"Helbig","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,3,25]]},"reference":[{"key":"bibr1-25158414241237713","doi-asserted-by":"crossref","DOI":"10.1136\/bmjophth-2020-000464","volume":"6","author":"Rossi T","year":"2021","journal-title":"BMJ Open Ophthalmol"},{"key":"bibr2-25158414241237713","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.05.011"},{"key":"bibr3-25158414241237713","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.04.032"},{"key":"bibr4-25158414241237713","doi-asserted-by":"publisher","DOI":"10.3390\/cryst12101418"},{"key":"bibr5-25158414241237713","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)00841-0"},{"key":"bibr6-25158414241237713","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700341"},{"key":"bibr7-25158414241237713","doi-asserted-by":"publisher","DOI":"10.21037\/atm-2020-rcs-16"},{"key":"bibr8-25158414241237713","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.04.009"},{"key":"bibr9-25158414241237713","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.87.6.800"},{"key":"bibr10-25158414241237713","doi-asserted-by":"publisher","DOI":"10.1039\/c2sm00011c"},{"key":"bibr11-25158414241237713","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics4020252"},{"key":"bibr12-25158414241237713","volume-title":"Paper presented at The American Society of Cataract and Refractive Surgery Annual Meeting","author":"Gartaganis P","year":"2023"}],"container-title":["Therapeutic Advances in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25158414241237713","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/25158414241237713","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25158414241237713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:40:31Z","timestamp":1777596031000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/25158414241237713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":12,"alternative-id":["10.1177\/25158414241237713"],"URL":"https:\/\/doi.org\/10.1177\/25158414241237713","relation":{},"ISSN":["2515-8414","2515-8414"],"issn-type":[{"value":"2515-8414","type":"print"},{"value":"2515-8414","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"25158414241237713"}}