{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:55:50Z","timestamp":1777881350783,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Interreg \u00d6resund-Kattegat-Skagerrak"},{"name":"Solar Foundation"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmol Eye Dis"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Age-related macular degeneration (AMD) is a prevalent cause of irreversible vision loss among the elderly. The prevalence and detailed characteristics of Charles Bonnet syndrome (CBS) remain largely unexplored in patients with geographic atrophy (GA) secondary to AMD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To investigate the prevalence and characteristics of CBS in patients with GA secondary to AMD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective cross-sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 149 patients with GA secondary to AMD were previously screened and examined for clinical studies. These patients were then prospective contacted by telephone for this study, and 120 patients responded and agreed to do an interview on symptoms of CBS. All with CBS were inquired about detailed characteristics of their hallucinations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Patients with GA secondary to AMD were aged 82.1\u2009\u00b1\u20096.2\u2009years and 62% were of female biological sex. The prevalence of CBS was 25 in 120 (20.8%). Thirteen (52%) of those with CBS were not previously informed of the disease. We found no difference between those with and without CBS in terms of age, biological sex, hearing difficulties, whether living alone or with others, co-morbidity of psychiatric or neurological diseases, or psychotropic use. Characteristics of the visual hallucinations were reported to occur at various frequencies from daily to less than monthly, occur during various times of the day, and almost always last minutes at most. Ten in 25 (40%) had not told anyone of having CBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>One in five with GA has CBS, which ranks GA as an eye disease with one of the highest reported prevalences of CBS. The condition presents with a significant variation across the patient group. A very large proportion of those with CBS were not informed of the disease and had never told anyone of their condition by their own initiative.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/25158414241305500","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T05:05:01Z","timestamp":1737003901000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Charles Bonnet syndrome in patients with geographic atrophy secondary to age-related macular degeneration: a cross-sectional study"],"prefix":"10.1177","volume":"17","author":[{"given":"Nathalie Skovgaard","family":"Eriksen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark"},{"name":"Department of Ophthalmology, Rigshospitalet, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabi","family":"Mousavi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark"},{"name":"Department of Ophthalmology, Rigshospitalet, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6620-5365","authenticated-orcid":false,"given":"Yousif","family":"Subhi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark"},{"name":"Department of Ophthalmology, Rigshospitalet, Copenhagen, Denmark"},{"name":"Department of Clinical Research, University of Southern Denmark, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torben Lykke","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark"},{"name":"Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3804-7296","authenticated-orcid":false,"given":"Marie","family":"Krogh Nielsen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark"},{"name":"Department of Ophthalmology, Rigshospitalet, Copenhagen, Denmark"},{"name":"Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(13)70145-1"},{"key":"e_1_3_4_3_2","article-title":"Prevalence of neovascular age-related macular degeneration and geographic atrophy in Denmark","volume":"64","author":"Sedeh FB","year":"2017","unstructured":"Sedeh FB, Scott DAR, Subhi Y, et al. Prevalence of neovascular age-related macular degeneration and geographic atrophy in Denmark. 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Low awareness of the Charles Bonnet syndrome in patients attending a retinal clinic. Dan Med J 2014; 61: A4770.","journal-title":"Dan Med J"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14567"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.03.006"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2021-319525"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-317237"},{"key":"e_1_3_4_20_2","article-title":"Practice patterns in reporting and documentation of Charles Bonnet syndrome: a retrospective review following COVID-19","volume":"16","author":"Abdulhussein D","year":"2024","unstructured":"Abdulhussein D, Jones L, Dintakurti SH, et al. Practice patterns in reporting and documentation of Charles Bonnet syndrome: a retrospective review following COVID-19. 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