{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:56:10Z","timestamp":1777881370015,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmol Eye Dis"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The Kahook Dual Blade (KDB) is a minimally invasive glaucoma surgery (MIGS) device designed to excise a strip of trabecular meshwork, enhancing aqueous outflow via Schlemm\u2019s canal. While its efficacy is well-documented, there is limited evidence comparing outcomes between anatomical quadrants treated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To compare intraocular pressure (IOP) reduction, medication burden, visual acuity improvement, and complication rates between nasal and inferior quadrant sectoral excisional goniotomy with KDB combined with cataract surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Medical records of patients with primary open-angle glaucoma who underwent combined phacoemulsification and KDB goniotomy between January 2020 and June 2025 at a single tertiary academic center were reviewed. Patients were grouped by treatment location (nasal vs inferior). Primary outcomes were IOP and the number of glaucoma medications; secondary outcomes included best-corrected visual acuity (BCVA) and adverse events. Multivariate linear regression was used to adjust for baseline differences between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Sixty-four eyes (nasal: 50; inferior: 14) met the inclusion criteria. Baseline IOP and BCVA were similar between groups, though the inferior group had fewer medications (1.93 vs 2.68;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.045) and milder visual field loss (MD \u22128.39 vs \u221215.18;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.04). Mean treatment extent was approximately 90\u00b0 in both groups. Both groups achieved significant IOP reduction at all follow-up points, with no long-term differences. At postoperative week 1, the inferior group had higher IOP (18.50 vs 13.99\u2009mmHg;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0433), potentially due to gravity-dependent hyphema. Medication burden decreased in both groups, with a non-significant trend toward fewer drops in the inferior group. BCVA improved similarly, and complication rates were low and comparable, with no serious adverse events.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Nasal and inferior quadrant KDB goniotomy combined with cataract surgery yields comparable long-term outcomes in IOP, medication burden, visual acuity, and safety. Quadrant selection may be guided by intraoperative visualization and patient-specific anatomy without compromising efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/25158414261437987","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T11:54:48Z","timestamp":1776686088000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Sectoral excisional goniotomy with Kahook Dual Blade: nasal versus inferior angle treatment"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4140-696X","authenticated-orcid":false,"given":"Iden","family":"Amiri","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Obi","family":"Wogu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Fleischman","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo","family":"Bonatti","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meredith R.","family":"Klifto","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of North Carolina-Chapel Hill, 2226 Nelson Hwy, Suite 220, Chapel Hill, NC 27517, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.05.013"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183142"},{"key":"e_1_3_4_4_2","first-page":"159","article-title":"Ab interno goniotomy\/goniectomy techniques","volume":"55","author":"Akta\u015f Z","year":"2025","unstructured":"Akta\u015f Z, Dorairaj S, Sayed M, et al. Ab interno goniotomy\/goniectomy techniques. Turk J Ophthalmol 2025; 55: 159","journal-title":"Turk J Ophthalmol"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-018-0755-4"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-024-03024-w"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40123-024-01016-8"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S451002"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-90223-5"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145824"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.01.030"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-14128"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S461830"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-024-01122-8"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2022.0098"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14603"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-024-06647-y"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-023-02704-3"},{"issue":"3","key":"e_1_3_4_20_2","article-title":"Medical interventions for traumatic hyphema","volume":"2023","author":"Woreta FA","year":"2023","unstructured":"Woreta FA, Lindsley KB, Gharaibeh A, et al. Medical interventions for traumatic hyphema. Cochrane Database Syst Rev 2023; 2023(3): CD005431.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_4_21_2","doi-asserted-by":"crossref","unstructured":"Gharaibeh A Savage HI Scherer RW et al. Medical interventions for traumatic hyphema. In: The Cochrane Collaboration (ed) Cochrane database of systematic reviews. Chichester UK: John Wiley & Sons Ltd 2011 p CD005431.pub2 https:\/\/doi.wiley.com\/10.1002\/14651858.CD005431.pub2 (2011 accessed 10 August 2025)","DOI":"10.1002\/14651858.CD005431.pub2"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S446486"}],"container-title":["Therapeutic Advances in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25158414261437987","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/25158414261437987","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/25158414261437987","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:41:04Z","timestamp":1777596064000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/25158414261437987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":21,"alternative-id":["10.1177\/25158414261437987"],"URL":"https:\/\/doi.org\/10.1177\/25158414261437987","relation":{},"ISSN":["2515-8414","2515-8414"],"issn-type":[{"value":"2515-8414","type":"print"},{"value":"2515-8414","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"article-number":"25158414261437987"}}