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Neuropsychological assessments [Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), Clinical Dementia Rating, Hamilton Anxiety Rating Scale (HAMA), Hamilton Depression Rating Scale (HAMD), Pittsburgh Sleep Quality Index) and resting-state electroencephalogram (rsEEG) were conducted at baseline, during treatment, and at 6-month follow-up. After treatment, MoCA and MMSE scores improved by 6 and 5 points; HAMA and HAMD scores declined by 7 and 3 points. rsEEG showed progressive increases in individual alpha peak frequency (8.69 to 10.22\u2005Hz), enhancement of alpha power, and reduction in theta power. Cerebrospinal fluid amyloid-\u03b2\n            <jats:sub>42<\/jats:sub>\n            levels also normalized. The patient reported marked mental well-being.\n          <\/jats:p>","DOI":"10.1177\/25424823251377988","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T17:52:41Z","timestamp":1758045161000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Integrating repetitive transcranial magnetic stimulation and Mediterranean diet for cognitive and anxiety improvement in early Alzheimer's disease: A case report and literature review"],"prefix":"10.1177","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4827-2052","authenticated-orcid":false,"given":"Yumei","family":"Liu","sequence":"first","affiliation":[{"name":"Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2238-0465","authenticated-orcid":false,"given":"Lin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5530-6539","authenticated-orcid":false,"given":"Zian","family":"Pei","sequence":"additional","affiliation":[{"name":"Department of Electronic and Electrical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2601-4246","authenticated-orcid":false,"given":"Zhifan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolin","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huixia","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhan","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyong","family":"Lan","sequence":"additional","affiliation":[{"name":"Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3843-8596","authenticated-orcid":false,"given":"Chongyuan","family":"Lian","sequence":"additional","affiliation":[{"name":"Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5307-7146","authenticated-orcid":false,"given":"Xue","family":"Shi","sequence":"additional","affiliation":[{"name":"Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2614-6118","authenticated-orcid":false,"given":"Yi","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China"},{"name":"Department of Neurology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,16]]},"reference":[{"key":"e_1_3_3_2_2","article-title":"Alzheimer's disease drug development pipeline: 2025","volume":"11","author":"Cummings JL","year":"2025","unstructured":"Cummings JL, Zhou Y, Lee G, et al. 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