{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:28:30Z","timestamp":1762957710631,"version":"build-2065373602"},"reference-count":46,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer's Disease Reports"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Instrumental Activities of Daily Living (IADL) are key indicators of functional decline in dementia, but culturally adapted tools for Latin America are scarce.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>This study aims to assess the validity and robustness of a new Peruvian version of the Amsterdam Instrumental Activities of Daily Living Questionnaire-Short Version (A-IADL-Q-SV-P).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We recruited 171 participants from a cognitive clinic in Peru (81 Clinical Dementia Rating (CDR)\u2009=\u20090, 70 CDR\u2009=\u20091, 20 CDR\u2009=\u20092), including 54 with Alzheimer's disease and 36 with frontotemporal dementia. Validity of the A-IADL-Q-SV-P was assessed using quadratic discriminant analysis to classify CDR level. Spearman correlations tested robustness with demographics (age, sex, education) and associations with cognitive (Mini-Mental State Examination), mood (Generalized Anxiety Disorder-7, Geriatric Depression Scale, and Neuropsychiatric Inventory), and functionality (Pfeffer Functional Activities Questionnaire and Technology-Activities of Daily Living Questionnaire) measures.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The A-IADL-Q-SV-P achieved excellent accuracy for classifying dementia severity (accuracy: 0.853, AUC\u2009&gt;\u20090.92). The ability to classify normal cognition had a sensitivity of 0.95 and a specificity of 0.91, and results were similar for patients with Alzheimer's disease or frontotemporal dementia (accuracy\u2009&gt;\u20090.88, sensitivity\u2009&gt;\u20090.95, and specificity\u2009&gt;\u20090.88, AUC\u2009&gt;\u20090.91). We also found weak associations with age, sex, and education (|rho|\u2009&lt;\u20090.2). Furthermore, the A-IADL-Q-SV-P had strong associations with other clinical scales (|rho|\u2009&gt;\u20090.4), particularly in relation to cognition (rho\u2009=\u2009\u22120.70) and functionality (rho\u2009&gt;\u20090.87).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>A-IADL-Q-SV-P demonstrated excellent accuracy in classifying dementia severity, with strong correlations to cognitive and other functionality measures. This supports the utility of A-IADL-Q-SV-P as a culturally adapted tool for assessing functional decline in dementia.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1177\/25424823251391360","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:24:14Z","timestamp":1761045854000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Adaptation and validations of Amsterdam instrumental activities of daily living questionnaire-short version for Peru"],"prefix":"10.1177","volume":"9","author":[{"given":"Rosa","family":"Montesinos","sequence":"first","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"},{"name":"Centro de Investigaci\u00f3n del Envejecimiento, Universidad de San Mart\u00edn de Porres, La Molina, Peru"},{"name":"Research Unit, Equilibria, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4013-8405","authenticated-orcid":false,"given":"Gregory","family":"Brown","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"},{"name":"Department of Neurology, University of California, San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Huilca","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"},{"name":"Research Unit, Equilibria, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1445-7211","authenticated-orcid":false,"given":"Bel\u00e9n","family":"Custodio","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Malaga","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karol","family":"Lipa","sequence":"additional","affiliation":[{"name":"Cayetano Heredia Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1073-1961","authenticated-orcid":false,"given":"Diego","family":"Bustamante-Paytan","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Ag\u00fcero","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"},{"name":"Research Unit, Equilibria, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciet","family":"Verastegui","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"},{"name":"Research Unit, Equilibria, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zadith","family":"Yauri","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"},{"name":"Research Unit, Equilibria, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8025-3272","authenticated-orcid":false,"given":"Nilton","family":"Custodio","sequence":"additional","affiliation":[{"name":"Research Unit, Instituto Peruano de Neurociencias (IPN), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"15","article-title":"Actualizaci\u00f3n del DSM-5\u00ae septiembre 2016","author":"Asociaci\u00f3n Americana de Psiquiatr\u00eda","year":"2016","unstructured":"Asociaci\u00f3n Americana de Psiquiatr\u00eda. 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