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Region of interest and voxel-wise analyses were performed to compare A\u03b2 deposition and glucose metabolism patterns among the three study groups. Standardized uptake value ratios were calculated using brainstem as the reference region for\n                      <jats:sup>18<\/jats:sup>\n                      F-florbetapir and\n                      <jats:sup>18<\/jats:sup>\n                      F-FDG PET, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with CAA exhibited significantly higher\n                      <jats:sup>18<\/jats:sup>\n                      F-florbetapir uptake in the cerebellum, global cerebral cortex, and various cortical regions compared to CSs. Compared to patients with AD, those with CAA showed predominantly higher\n                      <jats:sup>18<\/jats:sup>\n                      F-florbetapir uptake in the cerebellum but lower uptake in the insular cortex and posterior cingulate gyrus. Glucose hypometabolism patterns in CAA did not differ significantly from those observed in AD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Distinct A\u03b2 deposition patterns, particularly the increased amyloid burden in the cerebellum, could serve as a valuable biomarker for differentiating CAA from AD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/25424823251409418","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T17:43:29Z","timestamp":1767030209000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Higher cerebellum florbetapir uptake in cerebral amyloid angiopathy compared to Alzheimer's disease: A dual florbetapir and FDG PET 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