{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T22:01:18Z","timestamp":1781215278470,"version":"3.54.1"},"reference-count":64,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the clinical, microbiological, and patient-reported outcome measures (PROMs) of Er:YAG laser and photobiomodulation (PBM) therapy compared with conventional mechanical debridement (MD) in the nonsurgical treatment of peri-implantitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Forty-five patients with peri-implantitis were randomly assigned to MD (control,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 24) or Er:YAG laser followed by PBM (test,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 21). Clinical parameters [probing depth (PD), bleeding on probing (BoP), clinical attachment level (CAL), plaque index, recession, suppuration] and levels of\n                      <jats:italic toggle=\"yes\">Porphyromonas gingivalis<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">Filifactor alocis<\/jats:italic>\n                      were assessed at baseline and 3 months. Treatment success, defined as PD \u2264 5 mm, BoP at \u2264 1 site, and absence of suppuration, was assessed at 3 months. PROMs, including postoperative pain, analgesic use, anesthesia requirement, and satisfaction, were recorded during the first postoperative week.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Both groups showed significant clinical improvement (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). The laser group demonstrated greater reductions in PD (\u22122.30 vs. \u22121.45 mm,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), BoP (\u221273.0% vs. \u221242.4%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.004), and CAL (\u22122.56 vs. \u22121.47 mm,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.001), with higher treatment success (81% vs. 42%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.007).\n                      <jats:italic toggle=\"yes\">P. gingivalis<\/jats:italic>\n                      decreased significantly only in the laser group (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.001), while F. alocis changes were not significant in both groups. PROMs favored the laser group, with lower postoperative pain, reduced analgesic use, and higher satisfaction (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      Adjunctive Er:YAG and PBM therapy improved clinical outcomes, reduced\n                      <jats:italic toggle=\"yes\">P. gingivalis<\/jats:italic>\n                      , and enhanced patient experience compared with MD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance:<\/jats:title>\n                    <jats:p>Er:YAG and PBM therapy may improve treatment success, enhance patient comfort, and support more predictable nonsurgical management of peri-implantitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/25785478261447960","type":"journal-article","created":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T08:27:51Z","timestamp":1778315271000},"page":"427-436","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Nonsurgical Treatment of Peri-Implantitis Using Er:YAG Laser (2940 nm) and Photobiomodulation: A Randomized Controlled Clinical Trial. Clinical, Microbiological, and Patient-Reported Outcome Measures"],"prefix":"10.1177","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3676-6050","authenticated-orcid":false,"given":"Chariklia","family":"Neophytou","sequence":"first","affiliation":[{"name":"Department of Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki."},{"name":"Research Methodology in Medicine and Health Sciences, Medical School, Aristotle University of Thessaloniki."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitra","family":"Sakellari","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Vouros","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8277-3300","authenticated-orcid":false,"given":"Theodora","family":"Slini","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Aristotle University of Thessaloniki."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-8237","authenticated-orcid":false,"given":"Serafeim","family":"Chaintoutis","sequence":"additional","affiliation":[{"name":"Microbiology, Immunology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7415-3582","authenticated-orcid":false,"given":"Konstantinos","family":"Papadimitriou","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Implant Biology, School of Dentistry, Aristotle University of 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