{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:09:43Z","timestamp":1777882183459,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Palliat\ufffdCare"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Rates and patterns of inpatient palliative care (IPC) use in metastatic upper urinary tract carcinoma (mUTC) are largely unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To assess temporal trends and predictors of IPC in patients with mUTC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Relying on the National Inpatient Sample (2008\u20132019), we identified 3563 mUTC United States inpatients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Estimated annual percentage changes (EAPC) analyses as well as logistic regression models addressing IPC use were fitted. Subgroup analyses addressed IPC use according to the number and location of metastatic sites.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of 3563 mUTC inpatients, 540 (15%) received IPC. Overall, the rate of IPC increased from 2 to 22% between 2008 and 2019 (EAPC +10%). In subgroup analyses, the highest increase in IPC use was observed in patients with liver metastases (from 3 to 33%; EAPC + 11%), in patients with bone metastases (from 3 to 29%; EAPC: +10%), and in patients with three or more metastatic sites (from 0.5 to 31%; EAPC: 10%; all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009\u2a7d\u20090.003). In multivariable logistic regression models, liver metastases (odds ratio (OR) 1.91, 95% confidence interval (CI) 1.53\u20132.39), bone metastases (OR 1.83, 95% CI 1.46\u20132.28), and contemporary year of admission (OR 1.93, 1.57\u20132.38; all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) independently predicted higher IPC rates. Limitations include the retrospective nature of the inpatient database.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The IPC rate in mUTC was very low (15%). However, this rate increased to approximately 22% in 2019. The highest IPC rates were recorded in contemporary liver (33%), bone (29%), and three or more metastatic sites (31%) United States inpatients. Therefore, clinicians should be sensitized to early IPC use in mUTC patients in general as well as in other metastatic distribution patterns.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/26323524261416927","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:43:47Z","timestamp":1774356227000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal trends and predictors of inpatient palliative care in metastatic upper urinary tract carcinoma: An observational study"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5460-4171","authenticated-orcid":false,"given":"Carolin","family":"Siech","sequence":"first","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montr\u00e9al Health Center, QC, Canada"},{"name":"Goethe University Frankfurt, University Hospital, Department 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Experimental Oncology\/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy"},{"name":"Vita-Salute San Raffaele University, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letizia Maria Ippolita","family":"Jannello","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montr\u00e9al Health Center, QC, Canada"},{"name":"Department of Urology, IEO European Institute of Oncology, IRCCS, Milan, Italy"},{"name":"Universit\u00e0 degli Studi di Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Di Bello","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montr\u00e9al Health Center, QC, Canada"},{"name":"Department of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"Saad","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montr\u00e9al Health Center, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrokh F.","family":"Shariat","sequence":"additional","affiliation":[{"name":"Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Austria"},{"name":"Department of Urology, Weill Cornell Medical College, New York, NY, USA"},{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA"},{"name":"Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Longo","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Carmignani","sequence":"additional","affiliation":[{"name":"Department of Urology, IRCCS Policlinico San Donato, Milan, Italy"},{"name":"Department of Urology, IRCCS Ospedale Galeazzi \u2013 Sant\u2019Ambrogio, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ottavio","family":"de Cobelli","sequence":"additional","affiliation":[{"name":"Department of Urology, IEO European Institute of Oncology, IRCCS, Milan, Italy"},{"name":"Universit\u00e0 degli Studi di Milano, Italy"},{"name":"Department of Oncology and Haemato-Oncology, Universit\u00e0 degli Studi di Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sascha","family":"Ahyai","sequence":"additional","affiliation":[{"name":"Department of Urology, Medical University of Graz, 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