{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:19:44Z","timestamp":1777882784309,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Institut de Recerca Sant Pau"},{"name":"Bayer hispania S.L."}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Women's Health Reports"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The SAMANTA questionnaire and the Heavy Menstrual Bleeding\u2013Visual Analog Scale (HMB-VAS) tool have been validated for diagnosing heavy menstrual bleeding (HMB). We assessed their value for screening iron deficiency (ID).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods:<\/jats:title>\n                    <jats:p>Post hoc analysis of the prospective, randomized, phase 4 Cooper and Levonorgestrel Intrauterine Device (IUD) Barcelona Research Iniciative (COLIBRI) study, which assessed the bleeding profile of two intrauterine devices. We used information collected during the last follow-up visit (month 36): sociodemographics, hemoglobin\/ferritin levels, SAMANTA questionnaire, HMB-VAS tool, and EuroQoL five-dimension five-level scores. The primary outcome was the accuracy of these diagnostic tools in identifying ID. We also assessed their relationship with EQ-5D-5L.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We analyzed information from 57 women, 18 (31.6%) and 14 (24.6%) with HMB according to the SAMANTA questionnaire and the HMB-VAS tool, respectively. Ferritin levels showed better inverse correlation than hemoglobin with these HMB diagnostic tools\u2019 scores:\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.539 and\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.557, respectively, both\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001. In women with HMB according to these tools, the ferritin threshold showing the best sensitivity and specificity to identify ID was &lt;10 ng\/mL with the SAMANTA questionnaire (71.4% [Confidence Interval (CI) 95% 35.2\u201393.5] and 78% [CI 95% 65.2\u201387.7], respectively) and &lt;15 ng\/mL for the HMB-VAS tool (58.3% [CI 95% 31.2\u201387.7] and 82.2% [CI 95% 69.2\u201391.2], respectively). Only the EQ-VAS scores correlated inversely with the scores of both HMB diagnostic tools (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.308,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.02, and\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.294,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.026, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This exploratory analysis shows the SAMANTA questionnaire\u2019s good potential for ID screening. The scores of both HMB diagnostic tools correlated with the EQ-VAS, demonstrating their value in capturing the HMB impact on quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/26884844251382731","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T08:19:04Z","timestamp":1758874744000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Usefulness of the Heavy Menstrual Bleeding Diagnostic Tools SAMANTA Questionnaire and Heavy Menstrual Bleeding\u2013Visual Analog Scale Tool for Iron Deficiency Screening: An Exploratory Analysis from the COLIBRI Study"],"prefix":"10.1177","volume":"6","author":[{"given":"Josep","family":"Perell\u00f3-Cap\u00f3","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain."},{"name":"Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Estadella-Tarriel","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain."},{"name":"Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignasi","family":"Gich-Saladich","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Public Health Service, IIB Sant Pau, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Llurba-Oliv\u00e9","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain."},{"name":"Primary Care Interventions to Prevent Maternal and Child Chronic Diseases of Perinatal and Developmental Origin Network (RICORS), Instituto de Salud Carlos III, Madrid, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquim","family":"Calaf-Alsina","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain."},{"name":"Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"National Institute for Health and Care Excellence (NICE). Heavy Menstrual Bleeding: Assessment and Management. 2018. 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Haemoglobin Concentrations for the Diagnosis of Anaemia and Assessment of Severity. 2011. Available from: https:\/\/www.who.int\/publications\/i\/item\/WHO-NMH-NHD-MNM-11.1 [Last accessed: October21 2024]."},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1488"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(07)61235-5"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-019240"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.7861\/clinmed.2020-0582"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2023.110127"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2017.10.023"},{"key":"e_1_3_3_22_2","unstructured":"EuroQol Research Foundation. EQ-5D-5L User Guide. 2019. Available from: https:\/\/euroqol.org\/publications\/user-guides [Last accessed: October21 2024]."},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8510(90)90421-9"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogc.2017.11.036"},{"key":"e_1_3_3_25_2","unstructured":"Australian Commission on Safety and Quality in Health Care. Heavy Menstrual Bleeding Clinical Care Standard. 2017. [20 September 2024]. Available from: https:\/\/www.safetyandquality.gov.au\/standards\/clinical-care-standards\/heavy-menstrual-bleeding-clinical-care-standard [Last accessed: October21 2024]."},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003411"},{"key":"e_1_3_3_27_2","unstructured":"WHO. WHO Guideline on use of Ferritin Concentrations to assess Iron Status in Individuals and Populations. World Health Organization: Geneva; 2020. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789240000124 [Last accessed: October21 2024]."},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32594-0"},{"key":"e_1_3_3_29_2","unstructured":"Munro MG Boccia R Friedman AJ et al. Treatment for Iron Deficiency Anemia Associated with Heavy Menstrual Bleeding. 2019. Available from: https:\/\/www.mdedge.com\/obgyn\/article\/208888\/gynecology\/treatmentiron-deficiency-anemia-associated-heavymenstrual-bleeding. 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