{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:54:32Z","timestamp":1777643672549,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Facial Plastic Surgery &amp; Aesthetic Medicine"],"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Facial palsy in facioscapulohumeral muscular dystrophy (FSHD) significantly affects function and quality-of-life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To measure facial palsy burden in FSHD and assess its relationship to patient-reported outcomes and treatment-seeking behavior.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In a cross-sectional study, adults with FSHD completed FACE-Q (a validated patient-reported instrument assessing perceived facial appearance, function, and quality-of-life). A subset underwent objective facial movement analysis with DynaFace analysis software. Group differences in FACE-Q scores were compared between participants with\/without facial symptoms (Student\u2019s T-test), and Pearson correlations linked objective metrics to FACE-Q domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 191 respondents (mean age 52 \u00b1 16.5 years), those with facial symptoms (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 105) reported lower FACE-Q scores for smile, lips, appearance distress, and facial movement (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Participants who sought treatment reported greater appearance-related distress (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), yet overall treatment use was low, with 48% receiving eye care and 1% undergoing surgery. Objective analysis demonstrated reduced eye closure and diminished smile dynamics; abnormalities in dental display and commissure excursion correlated with worse FACE-Q scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Objective facial assessments revealed marked facial movement deficits in FSHD and were closely aligned with lower FACE-Q scores, implicating the functional and aesthetic burden of facial palsy in FSHD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/26893614251407675","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T09:52:24Z","timestamp":1770198744000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Facial Weakness in Facioscapulohumeral Muscular Dystrophy: Objective and Patient-Reported Measures to Guide Reconstructive Interventions"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0890-6291","authenticated-orcid":false,"given":"Alexandra J.","family":"Berges","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7211-4328","authenticated-orcid":false,"given":"Angela","family":"Renne","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Heaton","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Washington University, St. Louis, Missouri, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris G.","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA."},{"name":"Kennedy Krieger Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kofi D.O.","family":"Boahene","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880181315"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0960-8966(01)00201-2"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001783"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008123"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1101\/2025.02.19.639046"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-018-00675-3"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2022.2092779"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-10281-z"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/26893614251363957"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007013"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2022.2066208"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2012.12.001"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjhp.12440"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2005.09.003"},{"key":"e_1_3_2_16_2","article-title":"Use of dynamic, automated facial analysis in quantifying oral-ocular synkinesis","author":"Renne A","unstructured":"Renne A, , Heaton J, , Derakshan A, et al. Use of dynamic, automated facial analysis in quantifying oral-ocular synkinesis. Facial plastic surgery & aesthetic medicine. Accepted October 4, 2025.","journal-title":"Facial plastic surgery & aesthetic medicine"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000011924"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27964"},{"issue":"2","key":"e_1_3_2_19_2","first-page":"96","article-title":"Family context in muscular dystrophies: Psychosocial aspects and social integration","volume":"35","author":"Magliano L","year":"2016","unstructured":"Magliano L, , Politano L. Family context in muscular dystrophies: Psychosocial aspects and social integration. 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