{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:19:47Z","timestamp":1791418787721,"version":"4.3.3"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Hematology\/Oncology Nursing"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder characterized by overactivation of the immune system leading to disordered multiorgan inflammation. Allogeneic stem cell transplantation is the required curative treatment of primary HLH.\n                    <jats:bold>Method:<\/jats:bold>\n                    An infant prenatally diagnosed with HLH mutation presented with necrotic cellulitis. Our interdisciplinary team of specialists collaborated to implement early and aggressive supportive wound care strategies, including skin care for high-risk stem cell transplant patients.\n                    <jats:bold>Results:<\/jats:bold>\n                    The patient subsequently underwent allogeneic stem cell transplant with minimal complications and positive outcomes, despite entering the transplant with open skin lesions.\n                    <jats:bold>Discussion:<\/jats:bold>\n                    This complex case highlights the efforts of a multidisciplinary team to partner with the family to provide supportive care to optimize wound healing and improve outcomes.\n                  <\/jats:p>","DOI":"10.1177\/27527530251356970","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T05:56:34Z","timestamp":1755669394000},"page":"202-209","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Cutaneous Manifestations in an Infant With Hemophagocytic Lymphohistiocytosis: Case Report"],"prefix":"10.1177","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3014-3096","authenticated-orcid":false,"given":"Nancy","family":"Kuntz","sequence":"first","affiliation":[{"name":"Hyundai Cancer Institute, Orange, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesa J.","family":"Grovas","sequence":"additional","affiliation":[{"name":"Children's Hospital of Orange County"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina","family":"Tang","sequence":"additional","affiliation":[{"name":"Children's Hospital of Orange County"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yostina","family":"Armanyous","sequence":"additional","affiliation":[{"name":"Children's Hospital of Orange County"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clay","family":"Hoerig","sequence":"additional","affiliation":[{"name":"University of Minnesota M Health Fairview Masonic Children's Hospital, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilibeth","family":"Torno","sequence":"additional","affiliation":[{"name":"Hyundai Cancer Institute, Orange, CA, USA"},{"name":"University of California, Irvine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishi","family":"Chavan","sequence":"additional","affiliation":[{"name":"Hyundai Cancer Institute, Orange, CA, USA"},{"name":"University of California, Irvine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,8,19]]},"reference":[{"key":"e_1_3_2_2_1","first-page":"234","volume-title":"Essentials of pediatric hematology\/oncology nursing: A core curriculum","author":"Costello C.","year":"2014","unstructured":"Costello C. (2014). Skin changes. In Kline N. (Ed.), Essentials of pediatric hematology\/oncology nursing: A core curriculum (4th ed., pp. 234\u2013236). Association of Pediatric Hematology\/Oncology Nurses.","edition":"4"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2019.08.018"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09549.x"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-01322-6_9"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2021.07.031"},{"key":"e_1_3_2_7_1","doi-asserted-by":"crossref","unstructured":"Merli P. Algeri M. Gaspari S. & Locatelli F. (2020). Novel therapeutic approaches to familial HLH (Emapalumab in FHL). Frontiers in Immunology 11 608492.. https:\/\/doi.org\/10.3389\/fimmu.2020.608492","DOI":"10.3389\/fimmu.2020.608492"},{"key":"e_1_3_2_8_1","unstructured":"Negrin R. D. Rosman A. G. (2023). Preparative regimens for hematopoietic cell transplantation. UpToDate. Retrieved September 11 2023 from https:\/\/www.uptodate.com\/contents\/preparative-regimens-for-hematopoietic-cell-transplantation#references"},{"key":"e_1_3_2_9_1","article-title":"Wound healing in patients with cancer","volume":"8","author":"Payne W. G.","year":"2008","unstructured":"Payne W. G., Naidu D. K., Wheeler C. K., Barkoe D., Mentis M., Salas R. E., Smith D. J.Jr., Robson M. C. (2008). Wound healing in patients with cancer. Eplasty, 8, Article e9.","journal-title":"Eplasty"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2011.62"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/1078155218796905"}],"container-title":["Journal of Pediatric Hematology\/Oncology Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27527530251356970","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/27527530251356970","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27527530251356970","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:34:21Z","timestamp":1777509261000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/27527530251356970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1177\/27527530251356970"],"URL":"https:\/\/doi.org\/10.1177\/27527530251356970","relation":{},"ISSN":["2752-7530","2752-7549"],"issn-type":[{"value":"2752-7530","type":"print"},{"value":"2752-7549","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]}}}