{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:45:16Z","timestamp":1791834316410,"version":"4.3.4"},"reference-count":44,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Sigma Theta Tau, Alpha Alpha Lambda At-Large Research Award","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]},{"name":"Stanford Nurse Alumnae, Legacy Grant","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Hematology\/Oncology Nursing"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Port access can be a significant source of distress for pediatric oncology patients. This study sought to identify whether essential oil aromatherapy effectively reduces anxiety and pain associated with port access for pediatric oncology patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      This randomized control pilot study assigned participants (\n                      <jats:italic toggle=\"yes\">N<\/jats:italic>\n                      \u2009=\u200919) by age (4\u20138 years, 9\u201313 years, and 14\u201318 years) to either a control group who received standard of care (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200910) or an intervention group who received standard of care and aromatherapy (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20099), for a total of 49 control port accesses and 50 aromatherapy intervention port accesses. Participants reported anxiety using the Visual Facial Anxiety Scale on entering the Infusion Lab before port access. They reported pain after port access using either the 0\u201310 Likert scale or the Wong-Baker Faces Scale.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Younger participants (4\u20138 years) demonstrated a greater reduction in post-aromatherapy anxiety scores (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.008). Overall, no significant difference was observed in the reported post-port access pain scores of the intervention and control groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.7). Significant associations across all treatment groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and all age groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u2009.001) were found between post-intervention anxiety and post-access pain scores. The number of visits showed no significant associations with either post-aromatherapy pain (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.6) or anxiety scores (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.4).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Essential oil aromatherapy may effectively reduce reported anxiety scores among younger patients, though this study was underpowered due to its small sample size, and further research is needed to determine the extent of its efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/27527530261462142","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:55:12Z","timestamp":1791557712000},"page":"294-304","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the Efficacy of Essential Oil Aromatherapy on Children Undergoing Port Access: A Pilot Randomized Control Trial"],"prefix":"10.1177","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0649-0018","authenticated-orcid":false,"given":"Renee Allison","family":"Nolen","sequence":"first","affiliation":[{"name":"Stanford Medicine Children's Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keejeong","family":"Ryu","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Ritter","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5888-7738","authenticated-orcid":false,"given":"Robert","family":"Bennett","sequence":"additional","affiliation":[{"name":"Mayo Clinic Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette S.","family":"Nasr","sequence":"additional","affiliation":[{"name":"Stanford Medicine Children's Health"},{"name":"Stanford University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12910-020-0447-x"},{"key":"e_1_3_3_3_1","article-title":"The use of the buzzy, jet lidokaine, bubble-blowing and aromatherapy for reducing pediatric pain, stress and fear associated with phlebotomy","volume":"45","author":"Alemdar D. 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