{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:31:05Z","timestamp":1777883465157,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Chronic Disease"],"published-print":{"date-parts":[[2026,1]]},"abstract":"Summary<\/jats:title>\n \n Who should read this plain language summary?<\/jats:bold>\n <\/jats:p>\n This article may help people with chronic kidney disease, their families and other caregivers, patient advocates, and healthcare professionals to understand the effects of taking vicadrostat, given with or without empagliflozin, in people with chronic kidney disease.<\/jats:p>\n \n What is chronic kidney disease?<\/jats:bold>\n <\/jats:p>\n Chronic kidney disease (or CKD) is a condition where the kidneys are damaged and cannot filter blood properly. The most common causes of CKD are diabetes and hypertension.<\/jats:p>\n CKD varies in its severity and usually gets worse over time. CKD can progress to kidney failure in the most severe cases, although this does not happen in everyone with CKD.<\/jats:p>\n Further information on CKD, its diagnosis, and treatment options are shown below.<\/jats:p>\n \n Where can I find more information on CKD?<\/jats:bold>\n <\/jats:p>\n \n National Institute of Diabetes and Digestive and Kidney Diseases (US):\n https:\/\/www.niddk.nih.gov\/health-information\/kidney-disease\/chronic-kidney-disease-ckd<\/jats:ext-link>\n <\/jats:p>\n \n National Institute of Diabetes and Digestive and Kidney Diseases (US; Spanish language):\n https:\/\/www.kidney.org\/es\/kidney-topics\/pruebas-para-revisar-la-salud-renal<\/jats:ext-link>\n <\/jats:p>\n \n National Kidney Foundation (US):\n https:\/\/www.kidney.org\/kidney-topics\/chronic-kidney-disease-ckd<\/jats:ext-link>\n <\/jats:p>\n \n Kidney Care (UK):\n https:\/\/kidneycareuk.org\/kidney-disease-information\/kidney-conditions\/ckd-chronic-kidney-disease\/<\/jats:ext-link>\n <\/jats:p>","DOI":"10.1177\/27558428251411738","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T15:37:38Z","timestamp":1769182658000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Plain language summary of a publication: the effects of vicadrostat given with or without empagliflozin for treatment of chronic kidney disease"],"prefix":"10.1177","volume":"17","author":[{"given":"Katherine R.","family":"Tuttle","sequence":"first","affiliation":[{"name":"Providence Inland Northwest Health, University of Washington, Spokane, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Meyerhoff","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim International, Ingelheim am Rhein, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhichao","family":"Sun","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimoli V.","family":"Shah","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Rossing","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bill","family":"Wang","sequence":"additional","affiliation":[{"name":"Patient contributor, Hong Kong Kidney Foundation, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,23]]},"container-title":["Sage Open Chronic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27558428251411738","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/27558428251411738","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27558428251411738","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T01:46:49Z","timestamp":1777600009000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/27558428251411738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":0,"alternative-id":["10.1177\/27558428251411738"],"URL":"https:\/\/doi.org\/10.1177\/27558428251411738","relation":{},"ISSN":["2755-8428","2978-1558"],"issn-type":[{"value":"2755-8428","type":"print"},{"value":"2978-1558","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"article-number":"27558428251411738"}}