{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T18:15:50Z","timestamp":1789841750885,"version":"4.0.1"},"reference-count":34,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative and Complementary Medicine"],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Nonpharmacologic interventions have known benefits for managing chronic pain, particularly for conditions such as fibromyalgia, and are included in clinical guidelines. However, eye movement desensitization and reprocessing (EMDR) has not been established as a routine clinical practice for pain management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To systematically review the efficacy of EMDR for managing chronic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A search was conducted to identify randomized clinical trials (RCTs) and observational studies by using the keywords \u201cEMDR\u201d and \u201cchronic pain.\u201d Information was collected on the study population, EMDR protocol, methods for pain assessment, and outcomes. Risk of bias was evaluated, and intervention effect sizes were determined by calculating Hedges\n                      <jats:italic toggle=\"yes\">g<\/jats:italic>\n                      values for long-term follow-up data in RCTs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of nine studies, including seven RCTs, were reviewed. The studies used various diverse pain measurement tools and EMDR protocols. All reported significant improvements in pain symptoms with EMDR. Most of the studies reported statistically significant improvements in associated mental health issues, notably in psychological distress (four out of four studies), anxiety (three out of three studies), and depression (three out of four studies). Effect sizes varied among the studies, with three RCTs reporting large effects, two RCTs reporting moderate effects, and one RCT reporting small or nonsignificant effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>EMDR shows promise for managing chronic pain and addressing associated mental health symptoms. Despite study differences and limitations, the findings of this systematic review support the potential use of EMDR for chronic pain management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/27683605251362035","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T07:23:02Z","timestamp":1776669782000},"page":"1045-1055","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Eye Movement Desensitization and Reprocessing for Chronic Pain: A Systematic Review"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4643-431X","authenticated-orcid":false,"given":"Abhinav","family":"Singla","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA."},{"name":"Division of Hospital Internal Medicine, Mayo Clinic, Jacksonville, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pragyat","family":"Futela","sequence":"additional","affiliation":[{"name":"Maulana Azad Medical College, New Delhi, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komal","family":"Arora","sequence":"additional","affiliation":[{"name":"University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loren","family":"Toussaint","sequence":"additional","affiliation":[{"name":"Department of Psychology, Luther College, Decorah, Iowa, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaain","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Murawska Baptista","sequence":"additional","affiliation":[{"name":"Division of Hospital Internal Medicine, Mayo Clinic, Jacksonville, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher V.","family":"Anstine","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan T.","family":"Hurt","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey M.","family":"Philpot","sequence":"additional","affiliation":[{"name":"Division of Community Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA."},{"name":"Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arya B.","family":"Mohabbat","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,30]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6736a2"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2012.03.009"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2013.06.008"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2017.1336417"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007407.pub4"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/00207140701338621"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/jts.2490020207"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1037\/tra0000700"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-46138-0_13"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1891\/EMDR-2022-0017"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/16506073.2019.1703801"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12303"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/1078390316642519"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1891\/EMDR-D-20-00004"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1891\/EMDR-D-20-00036"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781119536604.ch8"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2016.00201"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/2156587216659400"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/MRR.0000000000000227"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S158981"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2024.1286118"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-019-04862-1"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.5350\/DAJPN2016290406"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2005.07.009"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0229228"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1891\/1933-3196.3.4.248"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1891\/1933-3196.13.4.337"},{"key":"e_1_3_4_30_2","first-page":"75","article-title":"EMDR treatment of fibromyalgia, a study of seven cases","volume":"13","author":"Kavak\u00e7\u0131 \u00d6","year":"2012","unstructured":"Kavak\u00e7\u0131 \u00d6, , Semiz M, , Kaptano\u011flu E, et al. 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