{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:05:35Z","timestamp":1777529135158,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative and Complementary Medicine"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We recently developed and established the feasibility of the first mind-body program aiming to prevent persistent concussion symptoms among young adults with anxiety \u2013 the Toolkit for Optimal Recovery after Concussion (TOR-C) and an active health education control (HE-C). Both interventions demonstrated preliminary improvements between baseline and post-intervention in outcomes including post-concussion symptoms, physical function, and anxiety. Here, we report on these outcomes 3 months post-intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Fifty young adults (ages 18\u201335) with a recent concussion (3\u201310 weeks) and anxiety (\u22655 on GAD-7) were randomized to TOR-C (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 25) or HE-C (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 25). Participants completed measures of concussion symptoms (PCSS), anxiety (GAD-7), and physical function (WHODAS 2.0) at baseline (pre-randomization), post-intervention, and 3 months post-intervention. We used mixed-model ANOVA with a shared baseline to adjust for baseline differences and assessed within-group changes in these outcomes from baseline to 3 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Preliminary improvements in concussion symptoms from baseline to 3 months post-intervention were statistically significant in both groups, but clinically meaningful (i.e., exceeding the Minimal Clinically Important Difference) only for TOR-C. Baseline versus 3-month follow-up improvements in physical function and anxiety were statistically significant and clinically meaningful for both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Findings provide preliminary evidence that TOR-C may help improve post-concussion recovery, and support a future fully-powered trial to establish the efficacy and sustained effects of TOR-C versus HE-C.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/27683605251363177","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T12:59:28Z","timestamp":1760619568000},"page":"932-934","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Concussion Outcomes 3 Months after an Intervention for Young Adults with Co-Occurring Anxiety: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1255-6125","authenticated-orcid":false,"given":"Nadine","family":"Levey","sequence":"first","affiliation":[{"name":"Center for Health Outcomes and Interdisciplinary Research, MA General Hospital, Boston, Massachusetts, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jafar","family":"Bakhshaie","sequence":"additional","affiliation":[{"name":"Center for Health Outcomes and Interdisciplinary Research, MA General Hospital, Boston, Massachusetts, USA."},{"name":"Harvard Medical School, Boston, Massachusetts, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3994-6488","authenticated-orcid":false,"given":"Ana-Maria","family":"Vranceanu","sequence":"additional","affiliation":[{"name":"Center for Health Outcomes and Interdisciplinary Research, MA General Hospital, Boston, Massachusetts, USA."},{"name":"Harvard Medical School, Boston, Massachusetts, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4875-2207","authenticated-orcid":false,"given":"Jonathan","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Center for Health Outcomes and Interdisciplinary Research, MA General Hospital, Boston, Massachusetts, USA."},{"name":"Harvard Medical School, Boston, Massachusetts, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20031988"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2014.3600"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/16501960410023732"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2020.08.014"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.2196\/25746"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2024.10.011"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/23259671221127049"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.01.032"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-220004"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2010.10.008"}],"container-title":["Journal of Integrative and Complementary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/27683605251363177","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27683605251363177","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27683605251363177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:38:22Z","timestamp":1777394302000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/27683605251363177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1177\/27683605251363177"],"URL":"https:\/\/doi.org\/10.1177\/27683605251363177","relation":{},"ISSN":["2768-3605","2768-3613"],"issn-type":[{"value":"2768-3605","type":"print"},{"value":"2768-3613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]}}}