{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T11:06:41Z","timestamp":1784027201971,"version":"3.55.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative and Complementary Medicine"],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Tobacco use is a leading cause of morbidity and mortality worldwide. Complementary therapies, such as auriculotherapy, are increasingly being explored for smoking cessation; however, inconsistent administration methods have limited definitive evidence. This study evaluated whether a single auriculotherapy session promotes smoking cessation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this multicenter, randomized, single-blind, superiority clinical trial conducted at a tertiary care university hospital and two private practices in France, we enrolled cigarette smokers aged \u226518 years who were motivated to quit. Participants were randomized into two groups using centralized computer-generated allocation: auriculotherapy (AUR) and sham auriculotherapy (SHAM). In the AUR group, specific ear points were treated with cryo-auriculotherapy (nitrous oxide gas applied for 2 sec). In the SHAM group, the same points were treated using an empty canister containing only a propellant gas. The participants were blinded to their group assignment. The primary outcome was the percentage of participants who achieved smoking cessation at 1 month, defined as a urinary cotinine level of &lt;50 \u03bcg\/L. Secondary outcomes included self-reported cessation, exhaled carbon monoxide levels, anxiety, depression, stress, weight gain, and auriculotherapy side effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Between November 16, 2021, and October 23, 2023, 90 participants were enrolled (45 in each group). The primary analysis included 36 participants in the AUR group and 32 in the SHAM group. Smoking cessation rates based on urinary cotinine &lt;50 \u03bcg\/L were similar: 18.8% (95% confidence interval [CI]: 0.09\u20130.35) in SHAM and 33.0% (95% CI: 0.20\u20130.50) in AUR (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.174). No significant adverse events or unintended effects were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A single cryo-auriculotherapy session did not significantly enhance smoking cessation compared with the sham session.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/27683605251415057","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T09:01:36Z","timestamp":1775552496000},"page":"601-610","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of a Single Auriculotherapy Session for Smoking Cessation: A Prospective, Randomized, Single-Blind, Superiority, Multicenter Trial"],"prefix":"10.1177","volume":"32","author":[{"given":"Mireille","family":"Michel-Cherqui","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, H\u00f4pital Foch, Suresnes, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, H\u00f4pital Foch, Suresnes, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Leroy","sequence":"additional","affiliation":[{"name":"Clinique La Sauvegarde, Lyon, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Chaix-Couturier","sequence":"additional","affiliation":[{"name":"Centre Medical de l\u2019Olivier, Montigny-le-Bretonneux, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Labro","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Data and Biostatistics, H\u00f4pital Foch, Suresnes, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pimnara","family":"Chuachao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Data and Biostatistics, H\u00f4pital Foch, Suresnes, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Christine","family":"Fagnen-Sylvaire","sequence":"additional","affiliation":[{"name":"Department of Addictology, H\u00f4pital Foch, Suresnes, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Le Guen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, H\u00f4pital Foch, Suresnes, France."},{"name":"Universit\u00e9 Paris-Saclay, Gif-sur-Yvette, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Fischler","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, H\u00f4pital Foch, Suresnes, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000146.pub4"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000146.pub5"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1590\/s0066-782x2007000400012"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2010.505130"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-12-11"},{"issue":"1","key":"e_1_3_3_7_2","first-page":"56","article-title":"Analysis of therapeutic effects of acupuncture on abstinence from smoking","volume":"14","author":"Jiang A","year":"1994","unstructured":"Jiang A, , Cui M. Analysis of therapeutic effects of acupuncture on abstinence from smoking. J Tradit Chin Med, 1994; 14(1):56\u201363.","journal-title":"J Tradit Chin Med"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1042\/cs20090264"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2013.01.120157"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.18295\/squmj.2021.21.02.017"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1726-4901(08)70014-5"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.11.015"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/bs7020037"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph13121236"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2016.0351"},{"key":"e_1_3_3_16_2","unstructured":"World Health Organization. Third WHO regional working group on the standardization of acupuncture nomenclature. 1987. Available from: https:\/\/iris.who.int\/handle\/10665\/254830. 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L\u2019auriculotherapie m\u00e9dicale: Bases scientifiques, Principes, Indications et Strat\u00e9gies Th\u00e9rapeutiques. (SAS EM., eds.) 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