{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T15:07:57Z","timestamp":1788188877260,"version":"build-2803163510"},"reference-count":58,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Research Foundation for Advanced Talents of Beijing Sport University","award":["3101037"],"award-info":[{"award-number":["3101037"]}]},{"name":"the Fundamental Research Funds for the Central Universities","award":["2025KYPT12"],"award-info":[{"award-number":["2025KYPT12"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative and Complementary Medicine"],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Depression is a common psychiatric disorder that impacts millions globally. Non-pharmacological treatments, such as combining music and exercise therapy, have shown potential as alternatives to medication. This meta-analysis evaluates the impact of integrating music with exercise on depressive symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A comprehensive literature search was conducted across multiple databases. Randomized controlled trials of combined music and exercise therapy for patients with mild, moderate, or severe depression were included. Interventions included any exercise paired with music therapy, such as Tai Chi or aerobics. They were compared with the standard of care, a waitlist control group, medication, and monotherapy. A meta-analysis was performed using random-effects models in RevMan 5.4. The standardized mean difference (SMD) was used as a summative measure. The effects of age, type of exercise, and duration of intervention on depression were explored in the subgroup analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Seven randomized controlled trials involving 640 patients with depression were analyzed. Results indicated significant improvement in depressive symptoms (SMD = \u22120.49, 95% CI: \u22120.93 to \u22120.06,\n                      <jats:italic toggle=\"yes\">p =<\/jats:italic>\n                      0.03). Subgroup analyses showed that music combined with Tai Chi (SMD = \u22120.96, 95% CI: \u22121.90 to \u22120.02,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.04) or aerobic exercise (SMD = \u22120.60, 95% CI: \u22120.98 to \u22120.23,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.001) over 12 weeks (SMD = \u22120.29, 95% confidence interval (CI): \u22120.50 to \u22120.08,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.008) significantly reduced symptoms, especially in patients older than 60 years (SMD = \u22120.31, 95% CI: \u22120.61 to \u22120.01,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.04). It can be suggested that patients with depression better tolerate music combined with exercise therapy. Two studies reported transient fatigue, and no withdrawals occurred due to adverse events.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This meta-analysis suggests that combining music and exercise therapy is effective in reducing depressive symptoms. Combining music with aerobic exercise and tai chi is particularly beneficial for patients over 60 years of age. The quality of the evidence was limited by the heterogeneity and varying risk of bias of the included studies, and caution is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/27683605261416759","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T12:31:53Z","timestamp":1770208313000},"page":"727-736","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Combined Music and Exercise Therapy on Depression: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"32","author":[{"given":"Xiaoqin","family":"Luo","sequence":"first","affiliation":[{"name":"Sports, Exercise and Brain Sciences Laboratory, Sports Coaching College, Beijing Sport University, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingyue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Sports, Exercise and Brain Sciences Laboratory, Sports Coaching College, Beijing Sport University, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmelo Mario","family":"Vicario","sequence":"additional","affiliation":[{"name":"Department of Cognitive Sciences, Psychology, Education and Cultural Studies, University of Messina, Messina, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhu","family":"Mei","sequence":"additional","affiliation":[{"name":"Sports, Exercise and Brain Sciences Laboratory, Sports Coaching College, Beijing Sport University, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengxue","family":"Qi","sequence":"additional","affiliation":[{"name":"Sports, Exercise and Brain Sciences Laboratory, Sports Coaching College, Beijing Sport University, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.62.6.593"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2005.04.012"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/58.3.m249"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/48.5.593"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-9-90"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e3181dc3a10"},{"issue":"4","key":"e_1_3_4_8_2","first-page":"522","article-title":"World health organization risk drinking levels among mandated college students: Associations with alcohol use, mental health, and academic performance","volume":"85","author":"Reid AE","year":"2024","unstructured":"Reid AE, , Cho GY, , Carey KB, et al. 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