{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:54:47Z","timestamp":1791046487321,"version":"4.1.0"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative and Complementary Medicine"],"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Postdischarge nausea and vomiting (PDNV) occur in up to 37% of surgical patients and increase readmissions. While acupuncture reduces postoperative nausea and vomiting (PONV), its effect on PDNV with standard prophylaxis is unclear. This study investigates whether acupuncture lowers PDNV incidence compared with sham treatment. Pain and POVN were secondary outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      This randomized, placebo-controlled, patient- and observer-blinded trial was conducted to determine whether acupuncture using three acupuncture points performed after surgery was an effective treatment in preventing PDNV compared with placebo. Patients (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 129) scheduled for arthroscopic knee surgery were randomly assigned to two groups receiving either acupuncture (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 69) or placebo (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 60). A prespecified subgroup analysis was conducted in 64 women, of whom 35 were allocated to the sham group and 31 to the acupuncture group. All adverse events (AEs), regardless of causality, were recorded and analyzed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result:<\/jats:title>\n                    <jats:p>\n                      The overall incidence of PDNV did not differ significantly between groups (6.17% acupuncture vs. 13.33% placebo,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.09). However, in the preplanned female subgroup, acupuncture significantly reduced PDNV compared with placebo (24% vs. 50%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.03). No significant difference between the groups regarding PONV or pain was detected. Only a few cases of AE were reported, and these were mild and self-limiting. No serious AEs were reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>There was no significant difference between acupuncture and placebo regarding PDNV. However, a significant reduction in PDNV was shown in the acupuncture group among females compared with placebo.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/27683605261492563","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:33:27Z","timestamp":1790861607000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A Comparison of Acupuncture Versus Placebo for Postdischarge Nausea and Vomiting Prophylaxis: A Randomized Placebo-Controlled, Patient- and Observer-Blinded Trial"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7980-8421","authenticated-orcid":false,"given":"Jacob","family":"Oxlund","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Esbjerg og Grindsted Sygehus, Esbjerg, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerda Dejgaard M\u00f8ller","family":"Kristensen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Esbjerg og Grindsted Sygehus, Esbjerg, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andra","family":"Pachai","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Esbjerg og Grindsted Sygehus, Esbjerg, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sine Skou","family":"Krogstrup","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Esbjerg og Grindsted Sygehus, Esbjerg, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina N\u00f8rskov","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Esbjerg og Grindsted Sygehus, Esbjerg, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette Vinther","family":"Riber","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmus Hjelmer","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Esbjerg og Grindsted Sygehus, Esbjerg, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0000000000001220"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.12921"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318267ef31"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-011-9660-x"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.10.037"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000007816"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/1075553041323894"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003281.pub5"},{"key":"e_1_3_2_10_1","volume-title":"Danish guidelines for the prevention and treatment of nausea and vomiting","author":"DASAIM","year":"2021","unstructured":"9.DASAIM. Vejledning i forebyggelse og behandling af kvalme og opkastning. In: Danish guidelines for the prevention and treatment of nausea and vomiting. DASAIM; 2021."},{"key":"e_1_3_2_11_1","article-title":"The selection rules of acupoints and meridians of traditional acupuncture for postoperative nausea and vomiting: A data mining-based literature study","author":"Li-Sha L","year":"2020","unstructured":"10.Li-Sha L, , Jian H, , Xiu-Li Y, et al. The selection rules of acupoints and meridians of traditional acupuncture for postoperative nausea and vomiting: A data mining-based literature study. Traditional Chinese Med 2020; doi: 10.53388\/TMR20200114154","journal-title":"Traditional Chinese Med"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-023-08289-y"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082474"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/aim.2010.003210"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/aim.20.4.168"},{"key":"e_1_3_2_16_1","article-title":"The effectiveness of participant blinding of non-penetrating sham\/placebo acupuncture in clinical trials: A systematic review with meta-analysis","author":"Gan YH","year":"2013","unstructured":"15.Gan YH, , Aye SN, , Suan SY. The effectiveness of participant blinding of non-penetrating sham\/placebo acupuncture in clinical trials: A systematic review with meta-analysis. PLoS One 2013; doi: 10.21203\/rs.3.rs-156277\/v1","journal-title":"PLoS One"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/185034"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199909000-00022"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12421"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2013.05.008"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03020521"}],"container-title":["Journal of Integrative and Complementary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27683605261492563","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/27683605261492563","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/27683605261492563","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:19:39Z","timestamp":1791044379000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/27683605261492563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,1]]},"references-count":20,"alternative-id":["10.1177\/27683605261492563"],"URL":"https:\/\/doi.org\/10.1177\/27683605261492563","relation":{},"ISSN":["2768-3605","2768-3613"],"issn-type":[{"value":"2768-3605","type":"print"},{"value":"2768-3613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,1]]},"article-number":"27683605261492563"}}