{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T10:47:01Z","timestamp":1782470821465,"version":"3.54.5"},"reference-count":42,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K12DA050607"],"award-info":[{"award-number":["K12DA050607"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K24DA056837"],"award-info":[{"award-number":["K24DA056837"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RM1DA055311"],"award-info":[{"award-number":["RM1DA055311"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32 DA057926"],"award-info":[{"award-number":["T32 DA057926"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"national institute on drug abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Substance Use &amp; Addiction Journal"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>\n                    Individuals with opioid misuse (OM) or opioid use disorder (OUD) frequently have co-occurring chronic pain (CP). Services for these chronic conditions are commonly siloed in specialty treatment programs with few empirically demonstrated integrated interventions for patients with OM\/OUD+CP. This manuscript describes the Tailored Retention and Engagement for Effective-integrated Treatment of OUD and Pain (TREETOP) engagement clinical trial protocol testing the effectiveness of a pain self-management (PSM) intervention at improving outcomes for patients with OM\/OUD+CP in the context of primary care settings. This is a multisite hybrid type-1 effectiveness-implementation clinical trial (n\u2009=\u2009228) wherein stratified equal randomization is used to assign participants to either PSM or usual care. The PSM intervention is novel because it was tailored to patients with OM\/OUD+CP and is delivered remotely by a trained interventionist over ten 1-hour sessions. All study activities are conducted virtually, and follow-up study visits occur at 3-, 6- and 9-months. Enhanced technology-based recruitment strategies are used to boost accrual. The primary outcome is reduction in pain interference (PROMIS SF v1.0\u2014Pain Interference 4a) at 3-months and secondary outcomes include pain self-efficacy (PSEQ), medications for opioid use disorder engagement and illicit drug use (Modified ASI). The supplemental protocol provides in-depth information on the study design and methods. Implementation measures are specific to this trial, which are crucial for the understanding and advancement of the uptake of evidence-based practices into everyday care. As part of the HEAL initiative\n                    <jats:sup>\u00ae<\/jats:sup>\n                    funded Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR) network, this randomized controlled trial will determine the effectiveness of an integrated PSM intervention for patients with OM\/OUD+CP, which has the potential to broadly reach under-served populations given its remote delivery and linkage with primary care settings.\n                  <\/jats:p>","DOI":"10.1177\/29767342251414537","type":"journal-article","created":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T04:39:32Z","timestamp":1770439172000},"page":"910-916","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Study Protocol for a Pain Self-Management Intervention to Reduce Pain and Improve MOUD Engagement in Primary Care: A Randomized 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