{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T14:17:02Z","timestamp":1787926622292,"version":"build-2784847793"},"reference-count":19,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R61DA059889"],"award-info":[{"award-number":["R61DA059889"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Substance Use &amp; Addiction Journal"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Substandard practices in opioid treatment programs (OTPs) contribute to missed doses and treatment discontinuation. Training OTP staff to deliver trauma-informed methadone treatment can facilitate the adoption of patient-centered practices and improve patient methadone access and use. A clinic-level, multimodal intervention to promote patient-centered methadone care was pilot-tested in 2 Arizona OTP clinics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A single-arm, repeated measures pilot trial consisting of 1.5 months preintervention onboarding and 4 months intervention and data collection was conducted from September 2024 to March 2025. Consistent daily methadone adherence was the primary outcome. Data were collected from patients (n = 91) in surveys at baseline and monthly thereafter. Bayesian multilevel generalized linear mixed models estimated the changes in consistent daily dosing from baseline (preintervention) to study conclusion (postintervention).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Patients had a greater likelihood of consistent daily methadone adherence in the past 30 days at study endpoint compared to baseline (adjusted odds ratio 3.63 [95% credible interval 1.27-10.60]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Findings from this exploratory study indicate the potential of this clinic-level intervention to support more consistent methadone use. Interpretive caution is advised as this is a single-arm design with study attrition, and limited follow-up period. Future studies will assess the effectiveness of this intervention in a large-scale, multisite randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/29767342261476896","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T09:06:24Z","timestamp":1787648784000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A Clinic-Level Intervention May Promote Methadone Patients\u2019 Consistent Daily Adherence to Their Dosing Schedules"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2084-9741","authenticated-orcid":false,"given":"Alissa","family":"Davis","sequence":"first","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"School of Social Work, Columbia University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Crosby","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"College of Public Health, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A.","family":"Carter","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"School of Nursing, Indiana University, Indianapolis, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sana","family":"Yousaf","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin R.","family":"Brady","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"School of Interdisciplinary Health Programs, Western Michigan University, Kalamazoo, MI, USA"},{"name":"Comprehensive Center for Pain and Addiction, University of Arizona, Tucson, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linnea B.","family":"Linde-Krieger","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"Comprehensive Center for Pain and Addiction, University of Arizona, Tucson, AZ, USA"},{"name":"School of Social Work, Arizona State University, Phoenix, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7957-6333","authenticated-orcid":false,"given":"Zhanette","family":"Coffee","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"Comprehensive Center for Pain and Addiction, University of Arizona, Tucson, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlene N.","family":"Mahoney","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"Southwest Recovery Alliance, Phoenix, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Frank","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"School of Global Public Health, New York University, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick S.","family":"Rivers","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"Department of Family and Community Medicine, University of Arizona College of Medicine, Tucson, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Drug Policy Research and Advocacy Board","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth E.","family":"Meyerson","sequence":"additional","affiliation":[{"name":"Harm Reduction Research Lab, University of Arizona College of Nursing, Tucson, AZ, USA"},{"name":"Comprehensive Center for Pain and Addiction, University of Arizona, Tucson, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/M17-3107"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-021-01764-9"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/10600280211028262"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12954-021-00535-y"},{"key":"e_1_3_3_6_2","unstructured":"The Pew Charitable Trusts. Overview of opioid treatment program regulations by state 2022. 2022. Accessed February 4 2025. https:\/\/pew.org\/3Qw8g8c"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.2196\/69829"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/29768357251383239"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1037\/trm0000566"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13722-024-00501-6"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/inm.12953"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.16918"},{"key":"e_1_3_3_13_2","unstructured":"National Archives. Code of Federal Regulations \u2013 title 42 part 8. 2024. Accessed September 10 2025. https:\/\/www.ecfr.gov\/current\/title-42\/chapter-I\/subchapter-A\/part-8"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1214\/08-AOAS191"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.3102\/1076998615621299"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v080.i01"},{"key":"e_1_3_3_17_2","unstructured":"R Core Team. A language and environment for statistical computing. 2024. Accessed November 18 2025. https:\/\/www.R-project.org\/"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.josat.2024.209616"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000001473"},{"key":"e_1_3_3_20_2","unstructured":"Ahmad F Cisewski J Rossen L Sutton P. Provisional Drug Overdose Death Counts. National Center for Health Statistics; 2024. Accessed December 6 2025. https:\/\/www.cdc.gov\/nchs\/nvss\/vsrr\/drug-overdose-data.htm"}],"container-title":["Substance Use &amp; Addiction Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/29767342261476896","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/29767342261476896","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/29767342261476896","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T13:17:26Z","timestamp":1787923046000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/29767342261476896"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,25]]},"references-count":19,"alternative-id":["10.1177\/29767342261476896"],"URL":"https:\/\/doi.org\/10.1177\/29767342261476896","relation":{},"ISSN":["2976-7342","2976-7350"],"issn-type":[{"value":"2976-7342","type":"print"},{"value":"2976-7350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,25]]},"article-number":"29767342261476896"}}