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Participants (N=280; ages 16\u201325) indicated number of close friends in their broad peer network who use nicotine vapes, and a subset reported on frequency of nicotine vaping among their 10 closest friends as well as frequency of vaping by their best friend. Analyses evaluated the effect of peer vaping on biochemically-verified 7-day nicotine abstinence (end-of-treatment and follow-up) and treatment adherence. Multilevel mixed-effects models accounted for treatment condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Participants reported a mean of 6.9 (\n                      <jats:italic toggle=\"yes\">SD<\/jats:italic>\n                      =6.8) close peers in their broad peer network used vaped nicotine at baseline; more peers using nicotine vapes was inversely associated with end-of-treatment abstinence (\u03b2=\u2212.11,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      =.03), and more frequent vaping among participants\u2019 top 10 closest peers and best friend vaping frequency were inversely associated with abstinence at end-of-treatment and follow-up (\u03b2s=\u2212.25 to \u2212.32,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      s\u2264.05). For every 1 SD increase in participants\u2019 best friend\u2019s vape frequency, participants were 76% less likely to maintain a vape quit at 3-month follow-up (\u03b2=\u20131.26,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      =.044; OR=0.24). Measures of peer vaping were also inversely associated with study medication adherence (\u03b2s&gt;=\u2212.52,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      s\u2264.007) and fewer counseling sessions attended (\u03b2s=\u2212.49 to \u2212.60,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      s\u2264.008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Peer vaping behavior may be associated with adolescents\u2019 capacity to quit vaped nicotine. Interventions that directly address peer network influences may enhance vaping cessation outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/29768357261481840","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:15:43Z","timestamp":1787940943000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Peer Vaped Nicotine Use in Adolescents and Young Adults: Associations With Abstinence and Intervention Adherence During a Quit Attempt"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9520-4676","authenticated-orcid":false,"given":"Meghan A.","family":"Costello","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"},{"name":"Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryn","family":"Evohr","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3979-4360","authenticated-orcid":false,"given":"Vanessa","family":"Iroegbulem","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Dufour","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3195-8349","authenticated-orcid":false,"given":"Kelly","family":"Casottana","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1516-0499","authenticated-orcid":false,"given":"Corinne","family":"Cather","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"},{"name":"Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gladys","family":"Pachas","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"},{"name":"Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5710-9301","authenticated-orcid":false,"given":"Randi M.","family":"Schuster","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA"},{"name":"Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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