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Resistance to antibiotics is a growing health problem, and healthcare authorities have warned that 10\u2009million people will die each year by 2050 and become the first killer. To date, resistance to vancomycin has not been recorded in Iraq. This study reports a 9-month-old infant presented with fever, irritability, crying, and decreased oral intake for 3\u2009days. Cerebrospinal fluid (CSF) parameters included turbid appearance, pleocytosis, and high protein and low sugar levels. Culture and sensitivity tests revealed the growth of Streptococcus pneumoniae, which is resistant to vancomycin. Reporting vancomycin resistance in Streptococcus pneumonia adds to the growing body of research on the pandemic of drug resistance. It indicates when all antibiotics are ineffective, as in the pre-antibiotic era, and this needs a more comprehensive plan.<\/jats:p>","DOI":"10.1177\/30502225251310515","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T04:57:51Z","timestamp":1739854671000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Vancomycin Resistance\n                    <i>Streptococcus pneumoniae<\/i>\n                    , a Case Report"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0533-8735","authenticated-orcid":false,"given":"Zana Baqi","family":"Najmadden","sequence":"first","affiliation":[{"name":"University of Halabja, Halabja, Kurdistan Region, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid Hama","family":"Salih","sequence":"additional","affiliation":[{"name":"University of Sulaimani, Sulaimani, Kurdistan, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihad Ibrahim","family":"Hama","sequence":"additional","affiliation":[{"name":"University of Halabja, Halabja, Kurdistan Region, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahmi Hussein","family":"Kakamad","sequence":"additional","affiliation":[{"name":"University of Sulaimani, Sulaimani, Kurdistan, Iraq"},{"name":"Smart Health Tower, Sulaimani, Kurdistan, Iraq"},{"name":"Kscien Organization for Scientific Research (Middle East office), Sulaimani, Kurdistan, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bakhtyar Qadr Hama","family":"Khurshid","sequence":"additional","affiliation":[{"name":"Pediatric Teaching Hospital, Sulaimani, Kurdistan, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"bibr1-30502225251310515","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6615334"},{"key":"bibr2-30502225251310515","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(05)01280-6"},{"key":"bibr3-30502225251310515","unstructured":"Pneumococcal conjugate vaccine for childhood immunization\u2013WHO position paper. 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